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Table 3 Homozygous and heterozygous of HLA-DRB1*07:01 and DRB1*12:02 in OBI carriers and controls

From: High resolution HLA-DRB1 analysis and shared molecular amino acid signature of DRβ1 molecules in Occult hepatitis B infection

HLA genotypes

OBI (GF%)

n = 107

Control (GF%)

n = 280

P

OR

95%CI

DRB1*07:01+/DRB1*07:01+

5 (4.67)

2 (0.71)

0.019

6.814

1.301–35.690

DRB1*07:01+/DRB1*07:01−

31 (28.97)

56 (20.00)

0.076

1.632

0.979–2.718

DRB1*07:01−/DRB1*07:01−

71 (66.36)

222 (79.39)

0.012

0.515

0.314–0.845

DRB1*12:02+/DRB1*12:02+

0

0

–

–

–

DRB1*12:02+/DRB1*12:02−

22 (20.56)

44 (15.71)

0.290

1.388

0.786–2.452

DRB1*12:02−/DRB1*12:02−

85 (79.44)

236 (84.29)

0.290

0.720

0.408–1.272

  1. OBI, occult hepatitis B infection; GF, gene frequency; OR, odds ratio; 95%CI, 95% confidence interval.
  2. In bold: significant value of Pc < 0.05
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BMC Immunology

ISSN: 1471-2172

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