Amino acid position | Amino acid variants | OBI (AA-F%) 2n = 214 | Control (AA-F%) 2n = 560 | p value | Pc | OR | 95% CI |
---|---|---|---|---|---|---|---|
4 | Glutamine (Q) | 76 (35.51) | 131 (23.39) | 0.0010 | 0.031 | 1.804 | 1.282–2.538 |
All others | 138 (64.49) | 429 (76.61) | |||||
11 | Glycine (G) | 41 (19.16) | 59 (10.54) | 0.0025 | 0.0775 | 2.012 | 1.303–3.108 |
All others | 173 (80.84) | 501 (89.46) | |||||
13 | Tyrosine (Y) | 41 (19.16) | 59 (10.54) | 0.0025 | 0.0775 | 2.012 | 1.303–3.108 |
All others | 173 (80.84) | 501 (89.46) | |||||
14 | Lysine (K) | 41 (19.16) | 59 (10.54) | 0.0025 | 0.0775 | 2.012 | 1.303–3.108 |
All others | 173 (80.84) | 501 (89.46) | |||||
25 | Glutamine (Q) | 41 (19.16) | 59 (10.54) | 0.0025 | 0.0775 | 2.012 | 1.303–3.108 |
All others | 173 (80.84) | 501 (89.46) | |||||
28 | Glutamic acid (E) | 81 (37.85) | 163 (29.11) | 0.0244 | 0.7564 | 1.483 | 1.065–2.065 |
All others | 133 (62.15) | 397 (70.89) | |||||
30 | Leucine (L) | 41 (19.16) | 59 (10.54) | 0.0025 | 0.0775 | 2.012 | 1.303–3.108 |
All others | 173 (80.84) | 501 (89.46) | |||||
37 | Phenylalanine (F) | 54 (25.23) | 92 (16.43) | 0.0074 | 0.2294 | 1.717 | 1.173–2.513 |
All others | 160 (74.77) | 468 (83.57) | |||||
57 | Valine (V) | 111 (51.87) | 205 (36.61) | 0.0002 | 0.0062 | 1.866 | 1.357–2.566 |
All others | 103 (48.13) | 355 (63.39) | |||||
60 | Serine (S) | 111 (51.87) | 205 (36.61) | 0.0002 | 0.0062 | 1.866 | 1.357–2.566 |
All others | 103 (48.13) | 355 (63.39) | |||||
73 | Glycine (G) | 51 (23.83) | 84 (15.00) | 0.0058 | 0.1798 | 1.762 | 1.192–2.604 |
All others | 164 (76.64) | 476 (85.00) | |||||
74 | Glutamine (Q) | 41 (19.16) | 59 (10.54) | 0.0025 | 0.0775 | 2.012 | 1.303–3.108 |
All others | 173 (80.84) | 501 (89.46) | |||||
78 | Valine (V) | 76 (35.51) | 131 (23.39) | 0.0010 | 0.031 | 1.804 | 1.282–2.538 |
All others | 138 (64.49) | 429 (76.61) |