Immune correlates of cardiovascular co-morbidity in HIV infected participants from South India

BMC Immunology

Table 4 Correlation coefficient of cardiac functional and arterial stiffness markers with T-cell immune activation in HIV + treatment naïve and on ART participants

Cardiac functional and arterial stiffness markers	Study groups	CD4 T−cell activation (CD4⁺ HLA−DR⁺ 38⁺)	CD8 T−cell activation (CD8⁺ HLA−DR⁺ 38⁺)
Estimated cardiac ejection time (msec)	Group 1	−0.341*	−0.212*
	Group 2	−0.036	−0.121
Estimated stroke volume (ml/beat)	Group 1	−0.378*	−0.241*
	Group 2	−0.048	−0.177*
Estimated stroke volume index (ml/beat/m²)	Group 1	−0.358*	−0.184
	Group 2	0.07	−0.117
Estimated cardiac output (L/min)	Group 1	−0.369*	−0.308*
	Group 2	−0.002	−0.089
Estimated cardiac index (L/min/m²)	Group 1	−0.328*	−0.226*
	Group 2	0.078	−0.009
Large artery elasticity index (ml/mmHg × 10)	Group 1	−0.192	−0.06
	Group 2	−0.069	−0.163*
Small artery elasticity index (ml/mmHg × 100)	Group 1	−0.076	−0.159
	Group 2	−0.017	−0.171*
Systemic vascular resistance (dyne.sec.cm⁻⁵)	Group 1	0.151	0.12
	Group 2	0.006	0.136
Total vascular impedance (dyne.sec.cm⁻⁵)	Group 1	0.12	0.086
	Group 2	0.025	0.113

Group 1; treatment Naïve participants , Group 2; Partcipants on ART
*Indicates statistically significant correlations. Spearman correlation was used to identify correlations

ISSN: 1471-2172