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Table 2 Differences in patient characteristics between CC-patients who expressed collagen-associated autoantibodies and those who did not

From: Lack of autoantibodies against collagen and related proteins in collagenous colitis

 

Antibodies, n = 18

No antibodies, n = 48

p-value

Mean age at inclusion (range)

59 (31–73)

61 (31–74)

0.36

Mean disease duration, years (range)

3.7 (1–14)

6.4 (1–22)

0.03

Smokers or former smokers (n, %)*

15 (83.3)

32 (66.7)

0.23

Budesonide treatment (n, %)

4 (22.2)

21 (43.4)

0.16

Past or current diseases: (n, %)

Reumatic disorder

3 (16.7)

7 (14.6)

1.0

Cancer

2 (11.1)

7 (14.6)

1.0

Asthma

2 (11.1)

7 (14.6)

1.0

Thyroid disorder

3 (16.7)

5 (10.4)

0.67

Celiac disease

1 (5.6)

2 (4.2)

1.0

  1. CC Collagenous colitis, * = missing value: 6, Collagen-associated autoantibodies = antibodies against collagen type III, collagen type IV, matrix metalloproteinase-9, tissue inhibitors of metalloproteinases-1, and tenascin-C. Student’s t-test was used to calculate differences between mean values. Fisher’s exact test was used to calculate the differences in frequency between groups