This section aims to publish studies concerned with the immunological activities of cells and on the interactions among cells and molecules of the immune system, which spans studies in development, differentiation, effector function, and memory. The section also welcomes submissions on antibody and cell-mediated immune responses.
The transmembrane domain and luminal C-terminal region independently support invariant chain trimerization and assembly with MHCII into nonamers
Invariant chain (CD74, Ii) is a multifunctional protein expressed in antigen presenting cells. It assists the ER exit of various cargos and serves as a receptor for the macrophage migration inhibitory factor. ...
Citation: BMC Immunology 2021 22:56