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BMC Immunology

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Cellular immunology and immune regulation

Section edited by J Philip McCoy

This section aims to publish studies concerned with the immunological activities of cells and on the interactions among cells and molecules of the immune system, which spans studies in development, differentiation, effector function, and memory. The section also welcomes submissions on antibody and cell-mediated immune responses.

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  1. Content type: Research article

    Bacterial genomes span a significant portion of diversity, reflecting their adaptation strategies; these strategies include nucleotide usage biases that affect chromosome configuration. Here, we explore an imm...

    Authors: Shireen Nigar, Yoshinari Yamamoto, Takuma Okajima, Suguru Shigemori, Takashi Sato, Tasuku Ogita and Takeshi Shimosato

    Citation: BMC Immunology 2017 18:44

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  2. Content type: Research article

    Epidemiological evidence and animal models suggest that exposure to low and non-neurotoxic concentrations of mercury may contribute to idiosyncratic autoimmune disease. Since defects in function and signaling ...

    Authors: Joseph A. Caruso, Nicholas Carruthers, Namhee Shin, Randal Gill, Paul M. Stemmer and Allen Rosenspire

    Citation: BMC Immunology 2017 18:37

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  3. Content type: Research article

    Type 1 diabetes is an autoimmune disease caused by T cell-mediated destruction of the insulin-producing β-cells in the pancreas. Therefore, approaches that effectively halt the pathogenic T cell response are p...

    Authors: Cristina Vazquez-Mateo, Justin Collins, Michelle Fleury and Hans Dooms

    Citation: BMC Immunology 2017 18:18

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  4. Content type: Research article

    Comprehensive understanding of cellular immune subsets involved in regulation of tumor progression is central to the development of cancer immunotherapies. Single cell immunophenotyping has historically been a...

    Authors: Elma Kadić, Raymond J. Moniz, Ying Huo, An Chi and Ilona Kariv

    Citation: BMC Immunology 2017 18:6

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  5. Content type: Research article

    The spleen is an important site for hematopoiesis. It supports development of myeloid cells from bone marrow-derived precursors entering from blood. Myeloid subsets in spleen are not well characterised althoug...

    Authors: Ying-Ying Hey, Benjamin Quah and Helen C. O’Neill

    Citation: BMC Immunology 2017 18:4

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  6. Content type: Research article

    CD4+CD25+ regulatory T (Treg) cells suppress tumor immunity by inhibiting immune cells. Manipulation of Treg cells represents a new strategy for cancer treatment. Zoledronic acid (ZA), a nitrogen-containing bisph...

    Authors: Hsien Liu, Shih-Han Wang, Shin-Cheh Chen, Ching-Ying Chen, Jo-Lin Lo and Tsun-Mei Lin

    Citation: BMC Immunology 2016 17:45

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  7. Content type: Methodology article

    The Luminex bead-based multiplex assay is useful for quantifying immune mediators such as cytokines and chemokines. Cross-comparisons of reagents for this technique from different suppliers have already been p...

    Authors: Mathieu Surenaud, Céline Manier, Laura Richert, Rodolphe Thiébaut, Yves Levy, Sophie Hue and Christine Lacabaratz

    Citation: BMC Immunology 2016 17:44

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  8. Content type: Research article

    Although histone methyltransferases EZH2 has been proved to have significant regulatory effect on the immune rejection after hematopoietic stem cell transplantation, its role in solid-organ transplantation rem...

    Authors: Long Li, Yi Zhang, Ming Xu, Ruiming Rong, Jina Wang and Tongyu Zhu

    Citation: BMC Immunology 2016 17:41

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  9. Content type: Research article

    Vaccination generating a robust memory population of CD8+ T cells may provide protection against cancer. However, immune therapies for cancer are influenced by the local tumour immune microenvironment. An infiltr...

    Authors: Andrew J. Highton, Adam Girardin, Georgia M. Bell, Sarah M. Hook and Roslyn A. Kemp

    Citation: BMC Immunology 2016 17:39

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  10. Content type: Research article

    Although Hizentra is indicated for immunoglobulin replacement therapy in patients with primary and secondary immunodeficiencies, phase III trials have focused on patients with primary immunodeficiencies. In th...

    Authors: J. F. Viallard, P. Agape, V. Barlogis, G. Cozon, C. Faure, F. Fouyssac, C. Gaud, M. P. Gourin, M. Hamidou, C. Hoarau, F. Husseini, M. Ojeda-Uribe, M. Pavic, I. Pellier, A. Perlat, N. Schleinitz…

    Citation: BMC Immunology 2016 17:34

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  11. Content type: Research article

    Recently, the immunostimulatory roles of chemotherapeutics have been increasingly revealed, although bone marrow suppression is still a common toxicity of chemotherapy. While the numbers and ratios of differen...

    Authors: Yanhong Wu, Zhenling Deng, Huiru Wang, Wenbo Ma, Chunxia Zhou and Shuren Zhang

    Citation: BMC Immunology 2016 17:29

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  12. Content type: Research article

    Capparis Spinosa L. is an aromatic plant growing wild in dry regions around the Mediterranean basin. Capparis Spinosa was shown to possess several properties such as antioxidant, antif...

    Authors: Mouna Moutia, Khadija El Azhary, Anass Elouaddari, Abdellah Al Jahid, Jamal Jamal Eddine, Fouad Seghrouchni, Norddine Habti and Abdallah Badou

    Citation: BMC Immunology 2016 17:26

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  13. Content type: Research article

    Major histocompatibility complex class I (MHCI) proteins present antigenic peptides for immune surveillance and play critical roles in nervous system development and plasticity. Most MHCI are transmembrane pro...

    Authors: Karla K. Frietze, Adlai L. Pappy II, Jack W. Melson, Emily E. O’Driscoll, Carolyn M. Tyler, David H. Perlman and Lisa M. Boulanger

    Citation: BMC Immunology 2016 17:24

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  14. Content type: Research article

    Adoptive transfer of genetically engineered autologous T-cells is becoming a successful therapy for cancer. The avidity of the engineered T-cells is of crucial importance for therapy success. We have in the pa...

    Authors: Victoria Hillerdal, Vanessa F. Boura, Hanna Björkelund, Karl Andersson and Magnus Essand

    Citation: BMC Immunology 2016 17:23

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  15. Content type: Research article

    Children are prone to get infections, especially in the respiratory system and the gut mainly because their immune system is immature. T cells significantly contribute to the prevention of infections, and diff...

    Authors: Erxia Shen, Mengjie Wang, Hairui Xie, Ruqiong Zou, Qiwen Lin, Lili lai, Fujun Li, Zhimei Liang, Yanran Xu and Maohua Zhou

    Citation: BMC Immunology 2016 17:20

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  16. Content type: Research article

    Inappropriate activation of T lymphocytes plays an important role in perinatal complications. However, data on T lymphocyte activation markers of preterm infants is scarce. We investigated the association betw...

    Authors: Florentina Sava, Gergely Toldi, András Treszl, Júlia Hajdú, Ágnes Harmath, Tivadar Tulassay and Barna Vásárhelyi

    Citation: BMC Immunology 2016 17:19

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  17. Content type: Research article

    Humanized mouse models are an increasingly popular preclinical model to study the human immune response in a biological system. There are a variety of protocols to generate these mice, each differing in the st...

    Authors: Crystal Dykstra, Amanda J. Lee, Evan J. Lusty, Mira M. Shenouda, Mahsa Shafai, Fatemeh Vahedi, Marianne V. Chew, Stephen Collins and Ali A. Ashkar

    Citation: BMC Immunology 2016 17:18

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2016 Journal Metrics

  • Citation Impact
    2.485 - 2-year Impact Factor
    2.454 - 5-year Impact Factor
    0.790 - Source Normalized Impact per Paper (SNIP)
    1.164 - SCImago Journal Rank (SJR)

    Usage 
    342,539 Downloads
    1280.5 Usage Factor

    Social Media Impact
    56 Mentions

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