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Articles

1080 result(s) for 'immunology' within BMC Immunology

Page 18 of 22

  1. Multiple sclerosis is a demyelinating and autoimmune disease and its immune response is not fully elucidated. This study was conducted to examine the pathological changes and B cell subsets in experimental aut...

    Authors: Yingqiong Xiong, Shaomin Cheng, Xiaomu Wu, Yue Ren and Xufang Xie
    Citation: BMC Immunology 2019 20:24
  2. Activation of integrins in response to inside-out signaling serves as a basis for leukocyte arrest on endothelium, and migration of immune cells. Integrin-dependent adhesion is controlled by the conformational...

    Authors: Alexandre Chigaev, Anna Waller, Or Amit and Larry A Sklar
    Citation: BMC Immunology 2008 9:26
  3. The human innate immune system uses a system of extracellular Toll-like receptors (TLRs) and intracellular Nod-like receptors (NLRs) to match the appropriate level of immune response to the level of threat fro...

    Authors: Andrei Y Istomin and Adam Godzik
    Citation: BMC Immunology 2009 10:48
  4. Antibody genes are diversified by somatic hypermutation (SHM), gene conversion and class-switch recombination. All three processes are initiated by the activation-induced deaminase (AID). According to a DNA de...

    Authors: Vladimir I Mayorov, Igor B Rogozin, Linda R Adkison, Christin Frahm, Thomas A Kunkel and Youri I Pavlov
    Citation: BMC Immunology 2005 6:10
  5. Cytomegalovirus seropositivity is an independent risk factor for atherosclerosis in patients with ESRD. Donor CMV seropositivity is associated with higher graft loss. Dendritic cells, macrophages and Th17 lymp...

    Authors: Mahmoud Sadeghi, Imad Lahdou, Gerhard Opelz, Arianeb Mehrabi, Martin Zeier, Paul Schnitzler and Volker Daniel
    Citation: BMC Immunology 2016 17:35
  6. Mutant peptides presented by cancer cells are superior vaccine candidates than self peptides. The efficacy of mutant K-Ras, P53 and EGFR (Epidermal Growth Factor Receptor) peptides have been tested as cancer v...

    Authors: Deng Pan, Dapeng Zhou, Weijing Cai, Weibo Wu, Wen Ling Tan, Caicun Zhou and Yanyan Lou
    Citation: BMC Immunology 2019 20:43
  7. While vaccination remains the most effective method to control hepatitis B virus (HBV) infection, 5–10% of recipients exhibit non-responsiveness to the HB vaccine. Immunological analysis of strong, weak or abs...

    Authors: Xiaojia Xu, Yulian Li, Yaping Liang, Mingjuan Yin, Zuwei Yu, Yan Zhang, Lingfeng Huang and Jindong Ni
    Citation: BMC Immunology 2018 19:25
  8. Human peripheral blood mononuclear cells (PBMCs) are extensively used for research of immune cell functions, identification of biomarkers and development of diagnostics and therapeutics for human diseases, amo...

    Authors: Adriana Navas, Lina Giraldo-Parra, Miguel Darío Prieto, Juliana Cabrera and María Adelaida Gómez
    Citation: BMC Immunology 2019 20:5
  9. Susceptibility to infectious diseases is directed, in part, by the interaction between the invading pathogen and host macrophages. This study examines the influence of genetic background on host-pathogen inter...

    Authors: Christine A Wells, Timothy Ravasi, Geoffrey J Faulkner, Piero Carninci, Yasushi Okazaki, Yoshihide Hayashizaki, Matthew Sweet, Brandon J Wainwright and David A Hume
    Citation: BMC Immunology 2003 4:5
  10. C5a is important for antineutrophil cytoplasmic antibody (ANCA)-mediated activation of neutrophils. The present study aimed to assess the role of macrophage migration inhibitory factor (MIF) in ANCA-mediated a...

    Authors: Jian Hao, Tiegang Lv, Liping Xu, Mao Ran and Kaili Wu
    Citation: BMC Immunology 2019 20:22
  11. Normal mammary gland contains an extravascular population of B lymphoblasts, precursors of the immunoglobulin plasma cells that play a key role in the passive protection of neonates by secreting immunoglobulin...

    Authors: Berardo de Jesus Rodriguez, Claire Chevaleyre, Gwénaële Henry, Daniel Mollé, Isabelle Virlogeux-Payant, Mustapha Berri, François Boulay, Joëlle Léonil, François Meurens and Henri Salmon
    Citation: BMC Immunology 2009 10:4
  12. Graft-versus-host disease (GVHD) is one of the most complex complications after allogeneic stem cell transplantation. Current standard of grading system is based on clinical symptoms in skin, liver and intesti...

    Authors: Ping Zhang, Shujun Yang, Yujing Zou, Xiao Yan, Hao Wu, Miao Zhou, Yong Cheng Sun, Yi Zhang, Huiling Zhu, Kaihong Xu, Yi Wang, Li Xia Sheng, Qitian Mu, Liguang Sun and Guifang Ouyang
    Citation: BMC Immunology 2019 20:46
  13. Chemokines and their cognate receptors play important role in the control of leukocyte chemotaxis, HIV entry and other inflammatory diseases. Developing an effcient method to investigate the functional express...

    Authors: Baosheng Ge, Jiqiang Li, Zhijin Wei, Tingting Sun, Yanzhuo Song and Naseer Ullah Khan
    Citation: BMC Immunology 2017 18:54
  14. Bacillus anthracis secretes several virulence factors targeting different host organs and cell types during inhalational anthrax infection. The bacterial expression of a key virulence factor, lethal toxin (LeTx) ...

    Authors: Christopher Bradburne, Myung-Chul Chung, Qin Zong, Karen Schlauch, Derong Liu, Taissia Popova, Anna Popova, Charles Bailey, Dan Soppet and Serguei Popov
    Citation: BMC Immunology 2008 9:67
  15. So-called "immunoprivileged sites" are tissues or organs where slow allograft rejection correlates with low levels of expression of MHC class I molecules. Whilst classical class I molecules are recognised by c...

    Authors: Pierre Lau, Claire Amadou, Hélène Brun, Virginie Rouillon, Fiona McLaren, Anne-France Le Rolle, Margaret Graham, Geoffrey W Butcher and Etienne Joly
    Citation: BMC Immunology 2003 4:7

    The Erratum to this article has been published in BMC Immunology 2004 5:4

  16. We have developed a cell-based vaccine that features the expression of both CD80 and CD86 on the surface of a murine neuroblastoma cell line. The cellular immunity induced by this vaccine is enhanced by treatm...

    Authors: Jin Zheng, M Eric Kohler, Qingrong Chen, James Weber, Javed Khan, Bryon D Johnson and Rimas J Orentas
    Citation: BMC Immunology 2007 8:4
  17. Regulatory CD4 T cells (Tregs) are critical in maintaining the homeostasis of the immune system. Quantitative or phenotypic alterations and functional impairment of Tregs have been associated with the developm...

    Authors: Raquel Matavele Chissumba, Suse Dayse Silva-Barbosa, Ângelo Augusto, Cremildo Maueia, Nédio Mabunda, Eduardo Samo Gudo Jr, Nilesh Bhatt, Ilesh Jani and Wilson Savino
    Citation: BMC Immunology 2015 16:52
  18. Inappropriate activation of T lymphocytes plays an important role in perinatal complications. However, data on T lymphocyte activation markers of preterm infants is scarce. We investigated the association betw...

    Authors: Florentina Sava, Gergely Toldi, András Treszl, Júlia Hajdú, Ágnes Harmath, Tivadar Tulassay and Barna Vásárhelyi
    Citation: BMC Immunology 2016 17:19
  19. Excretory-secretory products released by Echinococcus granulosus protoscoleces (EgPSC-ESPs) are well-known to regulate T cell responses. However, their direct influence on the differentiation of B cell subsets re...

    Authors: Wei Pan, Hui-wen Xu, Wen-ting Hao, Fen-fen Sun, Yan-fang Qin, Shan-shan Hao, Hua Liu, Jian-ping Cao, Yu-juan Shen and Kui-yang Zheng
    Citation: BMC Immunology 2018 19:29
  20. Intravesical Bacillus Calmette-Guerin (BCG) is an effective treatment for bladder superficial carcinoma and it is being tested in interstitial cystitis patients, but its precise mechanism of action remains poo...

    Authors: Marcia R Saban, Cindy Simpson, Carole Davis, Gemma Wallis, Nicholas Knowlton, Mark Barton Frank, Michael Centola, Randle M Gallucci and Ricardo Saban
    Citation: BMC Immunology 2007 8:6
  21. The balancing functions of pro/anti-inflammatory mediators of the complex innate responses have been investigated in a variety of experimental inflammatory settings. Annexin-A1 (AnxA1) is one mediator of endog...

    Authors: Amílcar S Damazo, André LF Sampaio, Cintia MAG Nakata, Roderick J Flower, Mauro Perretti and Sonia M Oliani
    Citation: BMC Immunology 2011 12:59
  22. Vaccination has been a major advance for health care, allowing eradication or reduction of incidence and mortality of various infectious diseases. However, there are major pathogens, such as Human Immunodefici...

    Authors: Mireille Centlivre and Béhazine Combadière
    Citation: BMC Immunology 2015 16:18
  23. Autoimmune diseases are more prevalent in females than in males, whereas males have higher mortality associated with infectious diseases. To increase our understanding of this sexual dimorphism in the immune s...

    Authors: Rebecca Lamason, Po Zhao, Rashmi Rawat, Adrian Davis, John C Hall, Jae Jin Chae, Rajeev Agarwal, Phillip Cohen, Antony Rosen, Eric P Hoffman and Kanneboyina Nagaraju
    Citation: BMC Immunology 2006 7:2
  24. Yersinia pestis, the etiological pathogen of plague, is capable of repressing the immune response of white blood cells to evade phagocytosis. The V-antigen (LcrV) was found to be involved in this process by bindi...

    Authors: Tiandi Wei, Jing Gong, Guojing Qu, Mingyu Wang and Hai Xu
    Citation: BMC Immunology 2019 20:48
  25. Activation of inflammasome contributes to the clearance of intracellular bacteria. C-terminus of E. coli EscI protein can activate NLRC4 (NLR family, CARD domain containing-4) inflammasome in macrophages. The pur...

    Authors: Maozhi Hu, Weixin Zhao, Wei Gao, Wenhua Li, Chuang Meng, Qiuxiang Yan, Yuyang Wang, Xiaohui Zhou, Shizhong Geng, Zhiming Pan, Guiyou Cui and Xinan Jiao
    Citation: BMC Immunology 2017 18:21
  26. Clonorchis sinensis infection could trigger strong immune responses in mice and humans. However, whether the C.sinensis infection has an impact on arthritis is unknown. Here we investigated the effect of C.sinens...

    Authors: Xiangyang Li, Ying Yang, Suping Qin, Fanyun Kong, Chao Yan, Wanpeng Cheng, Wei Pan, Qian Yu, Hui Hua, Kuiyang Zheng and Renxian Tang
    Citation: BMC Immunology 2020 21:7
  27. To investigate natural killer (NK) cell activity, circulating cytokine level and peripheral blood mononuclear cell (PBMC) cytokine production status in critically ill patients.

    Authors: Minkyung Kim, Minjoo Kim, Hana Jeong, Jey Sook Chae, Young Sam Kim, Jae Gil Lee, Younsoo Cho and Jong Ho Lee
    Citation: BMC Immunology 2017 18:48
  28. The immune reconstitution after initiation of highly active antiretroviral therapy (HAART) among HIV-infected individuals substantially affects patients’ prognosis. However, the dynamic characteristics and pre...

    Authors: Chong-Xi Li, Yu-Ye Li, Li-Ping He, Jing Kou, Jin-Song Bai, Jun Liu, Bo Tian, Li-Juan Cao, Kun-Hua Wang and Yi-Qun Kuang
    Citation: BMC Immunology 2019 20:31
  29. Mannose-binding lectin (MBL) deficiency may increase risk of respiratory tract infection in adults unselected for IgG or IgG subclass levels. In a retrospective study, we sought to determine associations of se...

    Authors: James C. Barton, Jackson C. Barton and Luigi F. Bertoli
    Citation: BMC Immunology 2019 20:15
  30. The B cell receptor (BCR) repertoire is highly diverse among individuals. Poor similarity of the spectrum among inbred baseline mice may limit the ability to discriminate true signals from those involving spec...

    Authors: Hongkai Wu, Zhichao Zhou, Shi Xie, Rong Yan, Mingxing Gong, Xingui Tian and Zhanhui Wang
    Citation: BMC Immunology 2022 23:11
  31. The regulatory processes that govern cell proliferation and differentiation are central to developmental biology. Particularly well studied in this respect is the lymphoid system due to its importance for basi...

    Authors: Ivan G Costa, Stefan Roepcke and Alexander Schliep
    Citation: BMC Immunology 2007 8:25
  32. Tuberculosis (TB) remains a serious human health problem that affects millions of people in the world. Understanding the biology of Mycobacterium tuberculosis (Mtb) is essential for tackling this devastating dise...

    Authors: Patricia Espinosa-Cueto, Marina Escalera-Zamudio, Alejandro Magallanes-Puebla, Luz María López-Marín, Erika Segura-Salinas and Raúl Mancilla
    Citation: BMC Immunology 2015 16:38
  33. Toxoplasma gondii is an opportunistic protozoan closely associated with AIDS and vertical transmission. T. gondii actin depolymerizing factor (TgADF) plays an important role in actin c...

    Authors: Zhuanzhuan Liu, Litian Yin, Yaqing Li, Fei Yuan, Xiaofan Zhang, Jiazhi Ma, Hongmei Liu, Yanjuan Wang, Kuiyang Zheng and Jianping Cao
    Citation: BMC Immunology 2016 17:37
  34. Neuromyelitis optica (NMO) is an autoimmune disorder of the central nervous system, which is characterized by autoantibodies directed against the water channel aquaporin-4 (AQP4). As one of the main water regu...

    Authors: Martin Juenemann, Tobias Braun, Simone Doenges, Max Nedelmann, Clemens Mueller, Georg Bachmann, Pratibha Singh, Franz Blaes, Tibo Gerriets and Marlene Tschernatsch
    Citation: BMC Immunology 2015 16:30
  35. Cytokines and chemokines are key mediators of anti-malarial immunity. We evaluated whether Intermittent Preventive Treatment in infants with Sulfadoxine-Pyrimethamine (IPTi-SP) had an effect on the acquisition...

    Authors: Diana Quelhas, Laura Puyol, Llorenç Quintó, Tacilta Nhampossa, Elisa Serra-Casas, Eusébio Macete, Pedro Aide, Sergi Sanz, John J Aponte, Denise L Doolan, Pedro L Alonso, Clara Menéndez and Carlota Dobaño
    Citation: BMC Immunology 2012 13:5
  36. Despite recent advances in early detection and improvements in chemotherapy for colon cancer, the patients still face poor prognosis of postoperative recurrence and metastasis, the median survival for patients...

    Authors: Huanyu Ju, Wenjing Xing, Jinfeng Yang, Yang Zheng, Xiuzhi Jia, Benning Zhang and Huan Ren
    Citation: BMC Immunology 2016 17:31
  37. Recent studies indicate a central role for the IL-23/IL-17 axis in the pathogenesis of lupus nephritis (LN) but the importance in the context of treatment outcome is unknown. We studied various cytokines, incl...

    Authors: Agneta Zickert, Petra Amoudruz, Yvonne Sundström, Johan Rönnelid, Vivianne Malmström and Iva Gunnarsson
    Citation: BMC Immunology 2015 16:7
  38. This study was performed to evaluate anti-inflammatory and immune modulating properties of the probiotic, spore-forming bacterial strain: Bacillus coagulans: GBI-30, (PTA-6086, GanedenBC30TM). In addition, cell w...

    Authors: Gitte S Jensen, Kathleen F Benson, Steve G Carter and John R Endres
    Citation: BMC Immunology 2010 11:15
  39. In comparison to higher vertebrates, fish are thought to rely heavily on innate immune system for initial protection against pathogen invasion because their acquired immune system displays a considerably poor ...

    Authors: Genciana Terova, Anna G Cattaneo, Elena Preziosa, Giovanni Bernardini and Marco Saroglia
    Citation: BMC Immunology 2011 12:69
  40. Subtype A is a major strain in the HIV-1 pandemic in eastern Europe, central Asia and in certain regions of east Africa, notably in rural Kenya. While considerable effort has been focused upon mapping and defi...

    Authors: Jeffrey R Currier, Unchalee Visawapoka, Sodsai Tovanabutra, Carl J Mason, Deborah L Birx, Francine E McCutchan and Josephine H Cox
    Citation: BMC Immunology 2006 7:8
  41. Non-alcoholic fatty liver disease (NAFLD) is a common, chronic liver disease worldwide. Recent studies have shown that T helper (Th) 17 and regulatory T (Treg) cells play critical roles in various disorders of...

    Authors: Beihui He, Liyan Wu, Wei Xie, Yitong Shao, Jianping Jiang, Zhenzhong Zhao, Maoxiang Yan, Zhiyun Chen and Dawei Cui
    Citation: BMC Immunology 2017 18:33
  42. Granulocyte-macrophage colony-stimulating factor (GM-CSF) has shown promising results as a cytokine adjuvant for antiviral vaccines and in various models of tumor gene therapy. To explore whether the targeting...

    Authors: Matthias Tenbusch, Seraphin Kuate, Bettina Tippler, Nicole Gerlach, Simone Schimmer, Ulf Dittmer and Klaus Überla
    Citation: BMC Immunology 2008 9:13
  43. Control of Mycobacterium tuberculosis (Mtb) infection requires CD4+ T-cell responses and major histocompatibility complex class II (MHC II) presentation of Mtb antigens (Ags). Dendritic cells (DCs) are the most p...

    Authors: Zhengzhong Xu, Aihong Xia, Xin Li, Zhaocheng Zhu, Yechi Shen, Shanshan Jin, Tian Lan, Yuqing Xie, Han Wu, Chuang Meng, Lin Sun, Yuelan Yin, Xiang Chen and Xinan Jiao
    Citation: BMC Immunology 2018 19:19
  44. Although Hizentra is indicated for immunoglobulin replacement therapy in patients with primary and secondary immunodeficiencies, phase III trials have focused on patients with primary immunodeficiencies. In th...

    Authors: J. F. Viallard, P. Agape, V. Barlogis, G. Cozon, C. Faure, F. Fouyssac, C. Gaud, M. P. Gourin, M. Hamidou, C. Hoarau, F. Husseini, M. Ojeda-Uribe, M. Pavic, I. Pellier, A. Perlat, N. Schleinitz…
    Citation: BMC Immunology 2016 17:34

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