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1171 result(s) for 'immunology' within BMC Immunology

Page 18 of 24

  1. Itch sensitization has been reported in patients with chronic allergic skin diseases and observed in a mouse model of allergic contact dermatitis (ACD). There is evidence suggesting that neuroimmune interactio...

    Authors: Tichakorn Singto, Viviane Filor, Jonathan Vidak, Robert Klopfleisch and Wolfgang Bäumer
    Citation: BMC Immunology 2024 25:17
    Content type: Research Published on:

  3. Mannose-binding lectin (MBL) plays an important role in the innate immune response by activating the complement system via the lectin pathway, and it has been studied in several viral infections; however, the ...

    Authors: Viviane Martha Santos de Morais, Juliana Prado Gonçales, Georgea Gertrudes de Oliveira Mendes Cahú, Tania Regina Tozetto-Mendoza and Maria Rosângela Cunha Duarte Coêlho
    Citation: BMC Immunology 2019 20:1
    Content type: Research article Published on:

  4. Leishmania parasites have been reported to interfere and even subvert their host immune responses to enhance their chances of survival and proliferation. Experimental Leishmania infection in mice has been widely ...

    Authors: Bernardo AS Pereira, Franklin S Silva, Karina M Rebello, Marcel Marín-Villa, Yara M Traub-Cseko, Thereza CB Andrade, Álvaro L Bertho, Ernesto R Caffarena and Carlos R Alves
    Citation: BMC Immunology 2011 12:44
    Content type: Research article Published on:

  6. Quantitative PCR (qPCR) is a powerful tool that is particularly well-suited to measure mRNA levels in clinical samples, especially those with relatively low cell counts. However, a caveat of this approach is t...

    Authors: Justin G. Roy, Janet E. McElhaney and Chris P. Verschoor
    Citation: BMC Immunology 2020 21:4
    Content type: Research article Published on:

  7. Malaria remains a major worldwide public health problem with ~207 million cases and ~627,000 deaths per year, mainly affecting children under five years of age in Africa. Recent efforts at elaborating a geneti...

    Authors: Audrey V Grant, Christian Roussilhon, Richard Paul and Anavaj Sakuntabhai
    Citation: BMC Immunology 2015 16:14
    Content type: Review Published on:

  8. Serological antibodies tests for tuberculosis (TB) are widely used in developing countries. They appear to have some advantages- faster, simple and could be used for extrapulmonary TB. However, most of current...

    Authors: Jinjing Tan, Xiaoguang Wu, Suting Chen, Meng Gu, Hairong Huang and Wentao Yue
    Citation: BMC Immunology 2018 19:10
    Content type: Research article Published on:

  9. High Immunoglobulin G (IgG) response to Plasmodium falciparum antigens is associated with partial malaria protection in sickle hemoglobin (HbS) children. However, this response has been more studied in children w...

    Authors: George Msema Bwire, Mtebe Majigo, Robert Makalla, Lillian Nkinda, Akili Mawazo, Mucho Mizinduko and Julie Makani
    Citation: BMC Immunology 2019 20:12
    Content type: Research article Published on:

  10. Discovery of tumor-selective antibodies or antibody fragments is a promising approach for delivering therapeutic agents to antigen over-expressing cancers. Therefore it is important to develop methods for the ...

    Authors: Ulrik B Nielsen, Dmitri B Kirpotin, Edward M Pickering, Daryl C Drummond and James D Marks
    Citation: BMC Immunology 2006 7:24
    Content type: Methodology article Published on:

  11. The most important factors that affect the incidence of vaccine-related complications are the constituent biological components of the vaccine, injection site reactions, age and sex. The aim of this study is t...

    Authors: Manoochehr Karami, Pegah Ameri, Jalal Bathaei, Zeinab Berangi, Tahereh Pashaei, Ali Zahiri, Seyed Mohsen Zahraei, Hussein Erfani and Koen Ponnet
    Citation: BMC Immunology 2017 18:42
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Immunology 2017 18:45

  14. Neutrophils induce the synthesis and release of angiopoietin 1 (Ang1), a cytosolic growth factor involved in angiogenesis and capable of inducing several pro-inflammatory activities in neutrophils. Neutrophils...

    Authors: Elcha Charles, Benjamin L. Dumont, Steven Bonneau, Paul-Eduard Neagoe, Louis Villeneuve, Agnès Räkel, Michel White and Martin G. Sirois
    Citation: BMC Immunology 2021 22:51
    Content type: Research Published on:

  16. Exposure of macrophages to bacterial products such as lipopolysaccharide (LPS) results in activation of the NF-κB transcription factor, which orchestrates a gene expression programme that underpins the macroph...

    Authors: Omar Sharif, Viacheslav N Bolshakov, Stephanie Raines, Peter Newham and Neil D Perkins
    Citation: BMC Immunology 2007 8:1
    Content type: Research article Published on:

  17. CD8α enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8α is also found on dendr...

    Authors: Derrick J Gibbings, Marcelo Marcet-Palacios, Yokananth Sekar, Marcus CY Ng and A Dean Befus
    Citation: BMC Immunology 2007 8:12
    Content type: Research article Published on:

  18. Several inflammatory cytokines play a key part in the induction of osteoporosis. Until now, involvement of the Th2 cytokine interleukin-31 (IL-31) in osteoporosis hadn’t yet been studied. IL-31 is a proinflamm...

    Authors: Lia Ginaldi, Massimo De Martinis, Fedra Ciccarelli, Salvatore Saitta, Selene Imbesi, Carmen Mannucci and Sebastiano Gangemi
    Citation: BMC Immunology 2015 16:60
    Content type: Research article Published on:

  19. Recent studies have focused on the significant cytotoxicity of natural killer (NK) cells, cytokine-induced killer (CIK) cells, and gamma-delta (γδ) T cells in tumor cells. Nevertheless, the therapeutic feature...

    Authors: Chao Niu, Haofan Jin, Min Li, Jianting Xu, Dongsheng Xu, Jifan Hu, Hua He, Wei Li and Jiuwei Cui
    Citation: BMC Immunology 2015 16:61
    Content type: Research article Published on:

  20. In certain cases, anti-idiotypic antibodies that recognize an antigen-combining site of an antibody can mimic the structure and/or function of certain nominal antigens. This feature makes them particularly use...

    Authors: Anja Colja Venturini, Maja Bresjanac, Tanja Vranac, Simon Koren, Mojca Narat, Mara Popović and Vladka Čurin Šerbec
    Citation: BMC Immunology 2009 10:16
    Content type: Research article Published on:

  21. It is well known that ABO blood group system incompatible kidney transplantation (ABOi-KT) is an effective strategy for end-stage renal disease. The main barrier for ABOi-KT is how to keep host B cell activati...

    Authors: Jingsong Cao, Luogen Liu, Yunsheng Zhang, Jianhua Xiao and Yi Wang
    Citation: BMC Immunology 2017 18:49
    Content type: Research article Published on:

  22. The persistent the inflammatory condition in multiple sclerosis (MS) may due to the aberrant regulation of the elimination of the pathogenic autoreactive lymphocytes through apoptosis. Survivin, encoded by the...

    Authors: Dariush Rahban, Forogh Mohammadi, Mehdi Alidadi, Taha Ghantabpour, Pedram Abbasi Ghasem Kheyli and Majid Ahmadi
    Citation: BMC Immunology 2019 20:30
    Content type: Research article Published on:

  23. Natural antibodies directed at carbohydrates reject porcine xenografts. They are initially expressed in germline configuration and are encoded by a small number of structurally-related germline progenitors. Th...

    Authors: Mary Kearns-Jonker, Natasha Barteneva, Robert Mencel, Namath Hussain, Irina Shulkin, Alan Xu, Margaret Yew and Donald V Cramer
    Citation: BMC Immunology 2007 8:3
    Content type: Research article Published on:

  24. Respiratory syncytial virus (RSV) infects the lung epithelium where it stimulates the production of numerous host cytokines that are associated with disease burden and acute lung injury. Characterizing the hos...

    Authors: Robert F Foronjy, Abdoulaye J Dabo, Neville Cummins and Patrick Geraghty
    Citation: BMC Immunology 2014 15:41
    Content type: Research article Published on:

  25. This study was designed to investigate the efficacy and safety of immune checkpoint inhibitors (ICIs)-based therapy in proficient mismatch repair (pMMR)/non-microsatellite instability-high (non-MSI-H) metastat...

    Authors: Qing Wu, Ziming Wang, Yang Luo and Xianhe Xie
    Citation: BMC Immunology 2023 24:27
    Content type: Research Published on:

  26. CD4+CD25+ regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several...

    Authors: Marta Barreto, Ricardo C Ferreira, Lara Lourenço, Maria F Moraes-Fontes, Eugénia Santos, Miguel Alves, Cláudia Carvalho, Berta Martins, Rita Andreia, João F Viana, Carlos Vasconcelos, Luísa Mota-Vieira, Carlos Ferreira, Jocelyne Demengeot and Astrid M Vicente
    Citation: BMC Immunology 2009 10:5
    Content type: Research article Published on:

  27. In coeliac disease, ingestion of gluten induces the production of transglutaminase 2 (TG2)-targeted autoantibodies by TG2-specific plasma cells present at high frequency in the small intestinal mucosa in untre...

    Authors: Minna Hietikko, Outi Koskinen, Kalle Kurppa, Kaija Laurila, Päivi Saavalainen, Teea Salmi, Tuire Ilus, Heini Huhtala, Katri Kaukinen and Katri Lindfors
    Citation: BMC Immunology 2018 19:36
    Content type: Research article Published on:

  28. Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells play an essential role in the host defence against intracellular pathogens such as Listeria, and Mycobacteria. The key mediator of bacteria-directed cyt...

    Authors: Michael Walch, Sonja Latinovic-Golic, Ana Velic, Hanna Sundstrom, Claudia Dumrese, Carsten A Wagner, Peter Groscurth and Urs Ziegler
    Citation: BMC Immunology 2007 8:14
    Content type: Research article Published on:

  29. Numerous data obtained by different research laboratories indicate that specific IgE production is triggered independently of specific IgG or IgA ones and so it is not linked to fully matured germinal centers ...

    Authors: Dmitrii Borisovich Chudakov, Dmitrii Yuryevich Ryasantsev, Daria Sergeevna Tsaregorotseva, Olga Dmitrievna Kotsareva, Gulnar Vaisovna Fattakhova and Elena Viktorovna Svirshchevskaya
    Citation: BMC Immunology 2020 21:45
    Content type: Research article Published on:

  30. Dendritic cells (DC) play a central role in primary immune responses and become potent stimulators of the adaptive immune response after undergoing the critical process of maturation. Understanding the dynamic...

    Authors: Amy L Olex, Elizabeth M Hiltbold, Xiaoyan Leng and Jacquelyn S Fetrow
    Citation: BMC Immunology 2010 11:41
    Content type: Research article Published on:

  32. The spread of a novel coronavirus termed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in China and other countries is of great concern worldwide with no effective vaccine. This study aimed to d...

    Authors: Yassir A. Almofti, Khoubieb Ali Abd-elrahman and Elsideeq E. M. Eltilib
    Citation: BMC Immunology 2021 22:22
    Content type: Research article Published on:

  33. Enprocal is a high-protein micro-nutrient rich formulated supplementary food designed to meet the nutritional needs of the frail elderly and be delivered to them in every day foods. We studied the potential of...

    Authors: Jagat R Kanwar and Rupinder K Kanwar
    Citation: BMC Immunology 2009 10:7
    Content type: Research article Published on:

  34. The zebrafish embryo is an important in vivo model to study the host innate immune response towards microbial infection. In most zebrafish infectious disease models, infection is achieved by micro-injection of ba...

    Authors: Joost J van Soest, Oliver W Stockhammer, Anita Ordas, Guido V Bloemberg, Herman P Spaink and Annemarie H Meijer
    Citation: BMC Immunology 2011 12:58
    Content type: Research article Published on:

  35. Inappropriate responses to normal intestinal bacteria may be involved in the development of Inflammatory Bowel Diseases (IBD, e.g. Crohn's Disease (CD), Ulcerative Colitis (UC)) and variations in the host geno...

    Authors: Matthew PG Barnett, Warren C McNabb, Adrian L Cookson, Shuotun Zhu, Marcus Davy, Bianca Knoch, Katia Nones, Alison J Hodgkinson and Nicole C Roy
    Citation: BMC Immunology 2010 11:39
    Content type: Research article Published on:

  36. Bladder cancer, cystitis and bladder polyp are the most common urinary system diseases all over the world. Our former research results show that IL-17A and IL-17 F contribute to the pathogenesis of benign pros...

    Authors: Yanbo Liu, Wanguo Yang, Lijing Zhao, Zuowen Liang, Weigao Shen, Qinlong Hou, Zhenjiang Wang, Jing Jiang and Sun Ying
    Citation: BMC Immunology 2016 17:36
    Content type: Research article Published on:

  37. Mitochondrial transcription factor A (TFAM) is associated with a number of neurodegenerative diseases and also with asthma. TFAM deficiency-induced mitochondrial DNA stress primes the antiviral innate immune r...

    Authors: Jinsong Luo, Hong Liu, Daniel K. Jun Li, Bin Song and Yi Zhang
    Citation: BMC Immunology 2021 22:74
    Content type: Research Published on:

  38. Cancer immunoprevention is based on the fact that a functioning immune system controls tumor onset and development in humans and animals, thus leading to the idea that the enhancement of immune responses in he...

    Authors: Arianna Palladini, Lorena Landuzzi, Pier-Luigi Lollini and Patrizia Nanni
    Citation: BMC Immunology 2018 19:16
    Content type: Review Published on:

  39. Tuberculosis (TB) is a major global public health problem. New treatment methods on TB are urgently demanded. In this study, Mycobacterium tuberculosis (MTB) rv2190c DNA vaccine was prepared and its immunogenicit...

    Authors: Yan Liang, Xiaoyan Zhang, Xuejuan Bai, Li Xiao, Xiaomei Wang, Junxian Zhang, Yourong Yang, Jinying Song, Lan Wang and Xueqiong Wu
    Citation: BMC Immunology 2017 18:11
    Content type: Research article Published on:

  40. TLR8 assists in antiviral approach by producing Type 1 INF via MyD88 dependent IRF7 pathway. However, over expression of INFα/β molecule poses threat by developing tolerance in chronic infection cases and enhanci...

    Authors: Anurag Adhikari, Birendra Prasad Gupta, Krishna Das Manandhar, Shravan Kumar Mishra, Hari Krishna Saiju, Rajendra Maan Shrestha, Nawneet Mishra and Shishir Sharma
    Citation: BMC Immunology 2015 16:42
    Content type: Research article Published on:

  41. The ability of anti-cytokine antibodies to play a disease-causing role in the pathogenesis of immunodeficiencies is widely accepted. The aim of this study was to investigate whether autoantibodies against BAFF...

    Authors: Marian-Christopher Pott, Natalie Frede, Jennifer Wanders, Lennart Hammarström, Erik-Oliver Glocker, Cristina Glocker, Fariba Tahami and Bodo Grimbacher
    Citation: BMC Immunology 2017 18:34
    Content type: Research article Published on:

  42. Previous studies have shown that γδ TFH cells are capable of modulating antibody production in immunized and infected mouse model. In recent studies, human γδ TFH cells are shown to contribute to the activatio...

    Authors: Wenjun Mou, Wei Han, Xiaoli Ma, Xiaolin Wang, Hong Qin, Wen Zhao, Xiaoya Ren, Xi Chen, Wei Yang, Haiyan Cheng, Xisi Wang, Hui Zhang, Xin Ni, Huanmin Wang and Jingang Gui
    Citation: BMC Immunology 2017 18:36
    Content type: Research article Published on:

  43. Vascular calcification is often associated with chronic inflammation and is a risk factor for brain arterial stiffness. Our previous results showed that miR32-5p was positively correlated with vascular smooth ...

    Authors: Jingsong Cao, Ling Chen, Xiaoling Zhong, Yingying Shen, Yan Gao, Qian Chen, Xuyu Zu and Jianghua Liu
    Citation: BMC Immunology 2020 21:3
    Content type: Research article Published on:

  44. Cystic echinococcosis, caused by infection with Echinococcus granulosus, is one of the most widespread zoonotic helminth diseases. Modulation of host responses is an important strategy used by helminth parasites ...

    Authors: Ying Wang, Hejun Zhou, Yujuan Shen, Yanjuan Wang, Weiping Wu, Haipeng Liu, Zhongying Yuan, Yuxin Xu, Yuan Hu and Jianping Cao
    Citation: BMC Immunology 2015 16:44
    Content type: Research article Published on:

  45. Human B cells and plasmacytoid dendritic cells (pDC) are the only cells known to express both TLR7 and TLR9. Plasmacytoid dendritic cells are the primary IFN-α producing cells in response to TLR7 and TLR9 agon...

    Authors: John A Hanten, John P Vasilakos, Christie L Riter, Lori Neys, Kenneth E Lipson, Sefik S Alkan and Woubalem Birmachu
    Citation: BMC Immunology 2008 9:39
    Content type: Research article Published on:

  46. Platelets are instrumental to primary haemostasis; in addition, as they are central to endothelium vascular repair, they play a role in physiological inflammation. Platelets have also been demonstrated to be k...

    Authors: Pauline Damien, Fabrice Cognasse, Marie-Ange Eyraud, Charles-Antoine Arthaud, Bruno Pozzetto, Olivier Garraud and Hind Hamzeh-Cognasse
    Citation: BMC Immunology 2015 16:3
    Content type: Research article Published on:

  47. To evaluate the impact of the duration of chronic inflammation on gene expression in skeletal muscle biopsies (MBx) from untreated children with juvenile dermatomyositis (JDM) and identify genes and biological...

    Authors: Yi-Wen Chen, Rongye Shi, Nicholas Geraci, Sheela Shrestha, Heather Gordish-Dressman and Lauren M Pachman
    Citation: BMC Immunology 2008 9:43
    Content type: Research article Published on:

  48. Egg white must provide nutrients and protection to the developing avian embryo. One way in which this is achieved is an arsenal of antimicrobial proteins and peptides which are essentially extensions of the in...

    Authors: Daoqing Gong, Peter W Wilson, Maureen M Bain, Karina McDade, Jiri Kalina, Virginie Hervé-Grépinet, Yves Nys and Ian C Dunn
    Citation: BMC Immunology 2010 11:12
    Content type: Research article Published on:

  49. Datura stramonium L. (Solanaceae) is used traditionally in west Africa to treat asthma, epilepsy, rheumatoid arthritis, filariasis microbial infections and conjunctivitis. This study investigated the immunomodula...

    Authors: Parker Elijah Joshua, Junaidu Yahaya, Daniel Emmanuel Ekpo, Joyce Oloaigbe Ogidigo, Arome Solomon Odiba, Rita Onyekachukwu Asomadu, Samson Ayodeji Oka and Olasupo Stephen Adeniyi
    Citation: BMC Immunology 2022 23:50
    Content type: Research Published on:

  50. In many clinical cases of extensive liver resection (e.g. due to malignancy), the residual portion is too small to maintain the body homeostasis. The resulting acute liver failure is associated with the compen...

    Authors: Andrey V. Elchaninov, Timur Kh. Fatkhudinov, Natalia Y. Usman, Evgeniya Y. Kananykhina, Irina V. Arutyunyan, Andrey V. Makarov, Anastasia V. Lokhonina, Irina Z. Eremina, Viktor V. Surovtsev, Dmitry V. Goldshtein, Galina B. Bolshakova, Valeria V. Glinkina and Gennady T. Sukhikh
    Citation: BMC Immunology 2018 19:23
    Content type: Research article Published on:

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BMC Immunology

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