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1170 result(s) for 'immunology' within BMC Immunology

Page 19 of 24

  1. We have developed a cell-based vaccine that features the expression of both CD80 and CD86 on the surface of a murine neuroblastoma cell line. The cellular immunity induced by this vaccine is enhanced by treatm...

    Authors: Jin Zheng, M Eric Kohler, Qingrong Chen, James Weber, Javed Khan, Bryon D Johnson and Rimas J Orentas
    Citation: BMC Immunology 2007 8:4
    Content type: Research article Published on:

  2. Several observations suggest that immunological events early after chemotherapy, possibly during the period of severe treatment-induced cytopenia, are important for antileukemic immune reactivity in acute myel...

    Authors: Elisabeth Ersvaer, Knut Liseth, Jørn Skavland, Bjørn Tore Gjertsen and Øystein Bruserud
    Citation: BMC Immunology 2010 11:38
    Content type: Research article Published on:

  3. Intravesical Bacillus Calmette-Guerin (BCG) is an effective treatment for bladder superficial carcinoma and it is being tested in interstitial cystitis patients, but its precise mechanism of action remains poo...

    Authors: Marcia R Saban, Cindy Simpson, Carole Davis, Gemma Wallis, Nicholas Knowlton, Mark Barton Frank, Michael Centola, Randle M Gallucci and Ricardo Saban
    Citation: BMC Immunology 2007 8:6
    Content type: Research article Published on:

  4. The balancing functions of pro/anti-inflammatory mediators of the complex innate responses have been investigated in a variety of experimental inflammatory settings. Annexin-A1 (AnxA1) is one mediator of endog...

    Authors: Amílcar S Damazo, André LF Sampaio, Cintia MAG Nakata, Roderick J Flower, Mauro Perretti and Sonia M Oliani
    Citation: BMC Immunology 2011 12:59
    Content type: Research article Published on:

  5. Autoimmune diseases are more prevalent in females than in males, whereas males have higher mortality associated with infectious diseases. To increase our understanding of this sexual dimorphism in the immune s...

    Authors: Rebecca Lamason, Po Zhao, Rashmi Rawat, Adrian Davis, John C Hall, Jae Jin Chae, Rajeev Agarwal, Phillip Cohen, Antony Rosen, Eric P Hoffman and Kanneboyina Nagaraju
    Citation: BMC Immunology 2006 7:2
    Content type: Research article Published on:

  6. The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this activation requires an interaction be...

    Authors: Mario Chamorro, Michael J Czar, Jayanta Debnath, Genhong Cheng, Michael J Lenardo, Harold E Varmus and Pamela L Schwartzberg
    Citation: BMC Immunology 2001 2:3
    Content type: Research article Published on:

  7. Intra-ductal cancer (IDC) is the most common type of breast cancer, with intra-lobular cancer (ILC) coming in second. Surgery is the primary treatment for early stage breast cancer. There are now irrefutable d...

    Authors: Hassan A. Saad, Azza Baz, Mohamed Riad, Mohamed E. Eraky, Ahmed El-Taher, Mohamed I. Farid, Khaled Sharaf, Huda E. M. Said and Lotfy A. Ibrahim
    Citation: BMC Immunology 2024 25:9
    Content type: Research Published on:

  8. The B cell receptor (BCR) repertoire is highly diverse among individuals. Poor similarity of the spectrum among inbred baseline mice may limit the ability to discriminate true signals from those involving spec...

    Authors: Hongkai Wu, Zhichao Zhou, Shi Xie, Rong Yan, Mingxing Gong, Xingui Tian and Zhanhui Wang
    Citation: BMC Immunology 2022 23:11
    Content type: Research Published on:

  9. Group 2 innate lymphoid cells (ILC2s) are the most dominant ILCs in heart tissue, and sex-related differences exist in mouse lung ILC2 phenotypes and functions; however, it is still unclear whether there are s...

    Authors: Hongyan Peng, Shuting Wu, Shanshan Wang, Qinglan Yang, Lili Wang, Shuju Zhang, Minghui Huang, Yana Li, Peiwen Xiong, Zhaohui Zhang, Yue Cai, Liping Li, Youcai Deng and Yafei Deng
    Citation: BMC Immunology 2022 23:52
    Content type: Research Published on:

  10. The regulatory processes that govern cell proliferation and differentiation are central to developmental biology. Particularly well studied in this respect is the lymphoid system due to its importance for basi...

    Authors: Ivan G Costa, Stefan Roepcke and Alexander Schliep
    Citation: BMC Immunology 2007 8:25
    Content type: Methodology article Published on:

  11. Cytokines and chemokines are key mediators of anti-malarial immunity. We evaluated whether Intermittent Preventive Treatment in infants with Sulfadoxine-Pyrimethamine (IPTi-SP) had an effect on the acquisition...

    Authors: Diana Quelhas, Laura Puyol, Llorenç Quintó, Tacilta Nhampossa, Elisa Serra-Casas, Eusébio Macete, Pedro Aide, Sergi Sanz, John J Aponte, Denise L Doolan, Pedro L Alonso, Clara Menéndez and Carlota Dobaño
    Citation: BMC Immunology 2012 13:5
    Content type: Research article Published on:

  12. This study was performed to evaluate anti-inflammatory and immune modulating properties of the probiotic, spore-forming bacterial strain: Bacillus coagulans: GBI-30, (PTA-6086, GanedenBC30TM). In addition, cell w...

    Authors: Gitte S Jensen, Kathleen F Benson, Steve G Carter and John R Endres
    Citation: BMC Immunology 2010 11:15
    Content type: Research article Published on:

  13. In comparison to higher vertebrates, fish are thought to rely heavily on innate immune system for initial protection against pathogen invasion because their acquired immune system displays a considerably poor ...

    Authors: Genciana Terova, Anna G Cattaneo, Elena Preziosa, Giovanni Bernardini and Marco Saroglia
    Citation: BMC Immunology 2011 12:69
    Content type: Research article Published on:

  14. Subtype A is a major strain in the HIV-1 pandemic in eastern Europe, central Asia and in certain regions of east Africa, notably in rural Kenya. While considerable effort has been focused upon mapping and defi...

    Authors: Jeffrey R Currier, Unchalee Visawapoka, Sodsai Tovanabutra, Carl J Mason, Deborah L Birx, Francine E McCutchan and Josephine H Cox
    Citation: BMC Immunology 2006 7:8
    Content type: Research article Published on:

  15. Granulocyte-macrophage colony-stimulating factor (GM-CSF) has shown promising results as a cytokine adjuvant for antiviral vaccines and in various models of tumor gene therapy. To explore whether the targeting...

    Authors: Matthias Tenbusch, Seraphin Kuate, Bettina Tippler, Nicole Gerlach, Simone Schimmer, Ulf Dittmer and Klaus Überla
    Citation: BMC Immunology 2008 9:13
    Content type: Research article Published on:

  17. CD146 is a well described homotypic adhesion molecule found on endothelial cells and a limited number of other cell types. In cells from the peripheral circulation, CD146 has also been reported to be on activa...

    Authors: Mohamed F Elshal, Sameena S Khan, Nalini Raghavachari, Yoshiyuki Takahashi, Jennifer Barb, James J Bailey, Peter J Munson, Michael A Solomon, Robert L Danner and J Philip McCoy Jr
    Citation: BMC Immunology 2007 8:29
    Content type: Research article Published on:

  18. Coccidioidomycosis or Valley fever is caused by a highly virulent fungal pathogen: Coccidioides posadasii or immitis. Vaccine development against Coccidioides is of contemporary interest because a large number of...

    Authors: Prachi Vilekar, Vibhudutta Awasthi, Pallavi Lagisetty, Catherine King, Nathan Shankar and Shanjana Awasthi
    Citation: BMC Immunology 2010 11:60
    Content type: Research article Published on:

  19. Modified Vaccinia Ankara (MVA) is a highly attenuated strain of vaccinia virus (VV) that has lost approximately 15% of the VV genome, along with the ability to replicate in most mammalian cells. It has demonst...

    Authors: Luzheng Liu, Rahul Chavan and Mark B Feinberg
    Citation: BMC Immunology 2008 9:15
    Content type: Research article Published on:

  20. Chronic inflammatory diseases, including diabetes and cardiovascular disease, are heterogeneous and often co-morbid, with increasing global prevalence. Uncontrolled type 2 diabetes (T2D) can result in severe i...

    Authors: Sarah E. Kleinstein, Jamison McCorrison, Alaa Ahmed, Hatice Hasturk, Thomas E. Van Dyke and Marcelo Freire
    Citation: BMC Immunology 2021 22:37
    Content type: Research article Published on:

  21. Dendritic cells (DCs) are antigen presenting cells capable of inducing innate and adaptive immune responses. According to the stimulus and their maturation state, DCs induce immunogenic or tolerogenic response...

    Authors: Hind Hamzeh-Cognasse, Fabrice Cognasse, Sabine Palle, Patricia Chavarin, Thomas Olivier, Olivier Delézay, Bruno Pozzetto and Olivier Garraud
    Citation: BMC Immunology 2008 9:54
    Content type: Research article Published on:

  22. The adenosine/uridine-rich element (ARE)-binding protein AUF1 functions to regulate the inflammatory response through the targeted degradation of cytokine and other mRNAs that contain specific AREs in their 3'...

    Authors: Navid Sadri, Jin-Yu Lu, Michelle L Badura and Robert J Schneider
    Citation: BMC Immunology 2010 11:1
    Content type: Research article Published on:

  23. The involvement of inflammasome activation and macrophage polarization during the process of syphilis infection remains unknown. In this study, A series of experiments were performed using human macrophages to...

    Authors: Li-Rong Lin, Wei Liu, Xiao-Zhen Zhu, Yu-Yan Chen, Zheng-Xiang Gao, Kun Gao, Man-Li Tong, Hui-Lin Zhang, Yao Xiao, Wen-Dong Li, Shu-Lian Li, Hui-Ling Lin, Li-Li Liu, Zan-Xi Fang, Jian-Jun Niu, Yong Lin…
    Citation: BMC Immunology 2018 19:28
    Content type: Research article Published on:

  25. Mannose-binding lectin (MBL) plays an important role in the innate immune response by activating the complement system via the lectin pathway, and it has been studied in several viral infections; however, the ...

    Authors: Viviane Martha Santos de Morais, Juliana Prado Gonçales, Georgea Gertrudes de Oliveira Mendes Cahú, Tania Regina Tozetto-Mendoza and Maria Rosângela Cunha Duarte Coêlho
    Citation: BMC Immunology 2019 20:1
    Content type: Research article Published on:

  26. Quantitative PCR (qPCR) is a powerful tool that is particularly well-suited to measure mRNA levels in clinical samples, especially those with relatively low cell counts. However, a caveat of this approach is t...

    Authors: Justin G. Roy, Janet E. McElhaney and Chris P. Verschoor
    Citation: BMC Immunology 2020 21:4
    Content type: Research article Published on:

  27. Malaria remains a major worldwide public health problem with ~207 million cases and ~627,000 deaths per year, mainly affecting children under five years of age in Africa. Recent efforts at elaborating a geneti...

    Authors: Audrey V Grant, Christian Roussilhon, Richard Paul and Anavaj Sakuntabhai
    Citation: BMC Immunology 2015 16:14
    Content type: Review Published on:

  28. Serological antibodies tests for tuberculosis (TB) are widely used in developing countries. They appear to have some advantages- faster, simple and could be used for extrapulmonary TB. However, most of current...

    Authors: Jinjing Tan, Xiaoguang Wu, Suting Chen, Meng Gu, Hairong Huang and Wentao Yue
    Citation: BMC Immunology 2018 19:10
    Content type: Research article Published on:

  29. High Immunoglobulin G (IgG) response to Plasmodium falciparum antigens is associated with partial malaria protection in sickle hemoglobin (HbS) children. However, this response has been more studied in children w...

    Authors: George Msema Bwire, Mtebe Majigo, Robert Makalla, Lillian Nkinda, Akili Mawazo, Mucho Mizinduko and Julie Makani
    Citation: BMC Immunology 2019 20:12
    Content type: Research article Published on:

  30. The most important factors that affect the incidence of vaccine-related complications are the constituent biological components of the vaccine, injection site reactions, age and sex. The aim of this study is t...

    Authors: Manoochehr Karami, Pegah Ameri, Jalal Bathaei, Zeinab Berangi, Tahereh Pashaei, Ali Zahiri, Seyed Mohsen Zahraei, Hussein Erfani and Koen Ponnet
    Citation: BMC Immunology 2017 18:42
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Immunology 2017 18:45

  34. Several inflammatory cytokines play a key part in the induction of osteoporosis. Until now, involvement of the Th2 cytokine interleukin-31 (IL-31) in osteoporosis hadn’t yet been studied. IL-31 is a proinflamm...

    Authors: Lia Ginaldi, Massimo De Martinis, Fedra Ciccarelli, Salvatore Saitta, Selene Imbesi, Carmen Mannucci and Sebastiano Gangemi
    Citation: BMC Immunology 2015 16:60
    Content type: Research article Published on:

  35. Recent studies have focused on the significant cytotoxicity of natural killer (NK) cells, cytokine-induced killer (CIK) cells, and gamma-delta (γδ) T cells in tumor cells. Nevertheless, the therapeutic feature...

    Authors: Chao Niu, Haofan Jin, Min Li, Jianting Xu, Dongsheng Xu, Jifan Hu, Hua He, Wei Li and Jiuwei Cui
    Citation: BMC Immunology 2015 16:61
    Content type: Research article Published on:

  36. It is well known that ABO blood group system incompatible kidney transplantation (ABOi-KT) is an effective strategy for end-stage renal disease. The main barrier for ABOi-KT is how to keep host B cell activati...

    Authors: Jingsong Cao, Luogen Liu, Yunsheng Zhang, Jianhua Xiao and Yi Wang
    Citation: BMC Immunology 2017 18:49
    Content type: Research article Published on:

  37. The persistent the inflammatory condition in multiple sclerosis (MS) may due to the aberrant regulation of the elimination of the pathogenic autoreactive lymphocytes through apoptosis. Survivin, encoded by the...

    Authors: Dariush Rahban, Forogh Mohammadi, Mehdi Alidadi, Taha Ghantabpour, Pedram Abbasi Ghasem Kheyli and Majid Ahmadi
    Citation: BMC Immunology 2019 20:30
    Content type: Research article Published on:

  38. In coeliac disease, ingestion of gluten induces the production of transglutaminase 2 (TG2)-targeted autoantibodies by TG2-specific plasma cells present at high frequency in the small intestinal mucosa in untre...

    Authors: Minna Hietikko, Outi Koskinen, Kalle Kurppa, Kaija Laurila, Päivi Saavalainen, Teea Salmi, Tuire Ilus, Heini Huhtala, Katri Kaukinen and Katri Lindfors
    Citation: BMC Immunology 2018 19:36
    Content type: Research article Published on:

  40. Bladder cancer, cystitis and bladder polyp are the most common urinary system diseases all over the world. Our former research results show that IL-17A and IL-17 F contribute to the pathogenesis of benign pros...

    Authors: Yanbo Liu, Wanguo Yang, Lijing Zhao, Zuowen Liang, Weigao Shen, Qinlong Hou, Zhenjiang Wang, Jing Jiang and Sun Ying
    Citation: BMC Immunology 2016 17:36
    Content type: Research article Published on:

  41. Cancer immunoprevention is based on the fact that a functioning immune system controls tumor onset and development in humans and animals, thus leading to the idea that the enhancement of immune responses in he...

    Authors: Arianna Palladini, Lorena Landuzzi, Pier-Luigi Lollini and Patrizia Nanni
    Citation: BMC Immunology 2018 19:16
    Content type: Review Published on:

  42. Tuberculosis (TB) is a major global public health problem. New treatment methods on TB are urgently demanded. In this study, Mycobacterium tuberculosis (MTB) rv2190c DNA vaccine was prepared and its immunogenicit...

    Authors: Yan Liang, Xiaoyan Zhang, Xuejuan Bai, Li Xiao, Xiaomei Wang, Junxian Zhang, Yourong Yang, Jinying Song, Lan Wang and Xueqiong Wu
    Citation: BMC Immunology 2017 18:11
    Content type: Research article Published on:

  43. TLR8 assists in antiviral approach by producing Type 1 INF via MyD88 dependent IRF7 pathway. However, over expression of INFα/β molecule poses threat by developing tolerance in chronic infection cases and enhanci...

    Authors: Anurag Adhikari, Birendra Prasad Gupta, Krishna Das Manandhar, Shravan Kumar Mishra, Hari Krishna Saiju, Rajendra Maan Shrestha, Nawneet Mishra and Shishir Sharma
    Citation: BMC Immunology 2015 16:42
    Content type: Research article Published on:

  44. The ability of anti-cytokine antibodies to play a disease-causing role in the pathogenesis of immunodeficiencies is widely accepted. The aim of this study was to investigate whether autoantibodies against BAFF...

    Authors: Marian-Christopher Pott, Natalie Frede, Jennifer Wanders, Lennart Hammarström, Erik-Oliver Glocker, Cristina Glocker, Fariba Tahami and Bodo Grimbacher
    Citation: BMC Immunology 2017 18:34
    Content type: Research article Published on:

  45. Previous studies have shown that γδ TFH cells are capable of modulating antibody production in immunized and infected mouse model. In recent studies, human γδ TFH cells are shown to contribute to the activatio...

    Authors: Wenjun Mou, Wei Han, Xiaoli Ma, Xiaolin Wang, Hong Qin, Wen Zhao, Xiaoya Ren, Xi Chen, Wei Yang, Haiyan Cheng, Xisi Wang, Hui Zhang, Xin Ni, Huanmin Wang and Jingang Gui
    Citation: BMC Immunology 2017 18:36
    Content type: Research article Published on:

  46. Vascular calcification is often associated with chronic inflammation and is a risk factor for brain arterial stiffness. Our previous results showed that miR32-5p was positively correlated with vascular smooth ...

    Authors: Jingsong Cao, Ling Chen, Xiaoling Zhong, Yingying Shen, Yan Gao, Qian Chen, Xuyu Zu and Jianghua Liu
    Citation: BMC Immunology 2020 21:3
    Content type: Research article Published on:

  47. Cystic echinococcosis, caused by infection with Echinococcus granulosus, is one of the most widespread zoonotic helminth diseases. Modulation of host responses is an important strategy used by helminth parasites ...

    Authors: Ying Wang, Hejun Zhou, Yujuan Shen, Yanjuan Wang, Weiping Wu, Haipeng Liu, Zhongying Yuan, Yuxin Xu, Yuan Hu and Jianping Cao
    Citation: BMC Immunology 2015 16:44
    Content type: Research article Published on:

  48. Platelets are instrumental to primary haemostasis; in addition, as they are central to endothelium vascular repair, they play a role in physiological inflammation. Platelets have also been demonstrated to be k...

    Authors: Pauline Damien, Fabrice Cognasse, Marie-Ange Eyraud, Charles-Antoine Arthaud, Bruno Pozzetto, Olivier Garraud and Hind Hamzeh-Cognasse
    Citation: BMC Immunology 2015 16:3
    Content type: Research article Published on:

  49. In many clinical cases of extensive liver resection (e.g. due to malignancy), the residual portion is too small to maintain the body homeostasis. The resulting acute liver failure is associated with the compen...

    Authors: Andrey V. Elchaninov, Timur Kh. Fatkhudinov, Natalia Y. Usman, Evgeniya Y. Kananykhina, Irina V. Arutyunyan, Andrey V. Makarov, Anastasia V. Lokhonina, Irina Z. Eremina, Viktor V. Surovtsev, Dmitry V. Goldshtein, Galina B. Bolshakova, Valeria V. Glinkina and Gennady T. Sukhikh
    Citation: BMC Immunology 2018 19:23
    Content type: Research article Published on:

  50. As a result of successful PMTCT programs, children born from HIV-infected mothers are now effectively protected from contracting the infection. However, it is not well known whether in utero exposure to the virus...

    Authors: Herbert Longwe, Kamija S. Phiri, Nyanyiwe M. Mbeye, Thandile Gondwe, Kondwani C. Jambo and Wilson L. Mandala
    Citation: BMC Immunology 2015 16:50
    Content type: Research article Published on:

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BMC Immunology

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