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1169 result(s) for 'immunology' within BMC Immunology

Page 22 of 24

  1. Pertussis (whooping cough) remains a public health problem despite extensive vaccination strategies. Better understanding of the host-pathogen interaction and the detailed B. pertussis (Bp) target recognition pat...

    Authors: Davide Valentini, Giovanni Ferrara, Reza Advani, Hans O Hallander and Markus J Maeurer
    Citation: BMC Immunology 2015 16:40
  2. Mycobacterium tuberculosis (M. tuberculosis) modulates host immune response, mainly T cell responses for its own survival leading to disease or latent infection. The molecules and mech...

    Authors: Bhawna Sharma, Rajni Upadhyay, Bhavyata Dua, Naim Akhtar Khan, Vishwa Mohan Katoch, Bharat Bajaj and Beenu Joshi
    Citation: BMC Immunology 2015 16:67
  3. While the 23-valent pneumococcal polysaccharide vaccine (PPV23) is routinely used in Canada and some other countries to prevent pneumococcal infection in adults with chronic kidney disease (CKD), patients deve...

    Authors: Gabrielle Nicole Gaultier, William McCready and Marina Ulanova
    Citation: BMC Immunology 2019 20:41
  4. Non-adherence has been associated with reduced graft survival. The aim of this study was to investigate the immunological mechanisms underlying chronic renal allograft rejection using a model of non-adherence ...

    Authors: Louisa Kühne, Bettina Jung, Helen Poth, Antonia Schuster, Simone Wurm, Petra Ruemmele, Bernhard Banas and Tobias Bergler
    Citation: BMC Immunology 2017 18:52
  5. Non-small cell lung cancer (NSCLC) remains the most common cause of cancer related death worldwide. Tumor-infiltrating macrophages are believed to play an important role in growth, progression, and metastasis ...

    Authors: Jurgita Jackute, Marius Zemaitis, Darius Pranys, Brigita Sitkauskiene, Skaidrius Miliauskas, Simona Vaitkiene and Raimundas Sakalauskas
    Citation: BMC Immunology 2018 19:3
  6. The Major Histocompatibility Complex (MHC) class I family of genes encode for molecules that have well-conserved structures, but have evolved to perform diverse functions. The availability of the gray, short-t...

    Authors: Katina V. Krasnec, Anthony T. Papenfuss and Robert D. Miller
    Citation: BMC Immunology 2016 17:43
  7. The small intestine is a specialized compartment were close interactions take place between host, microbes, food antigens and dietary fatty acids. Dietary fats get absorbed by epithelial cells and processed in...

    Authors: Jeroen van Bergenhenegouwen, Aletta D. Kraneveld, Lieke Rutten, Johan Garssen, Arjan P. Vos and Anita Hartog
    Citation: BMC Immunology 2016 17:42
  8. Mesenchymal stromal cells (MSCs) are multipotent progenitor cells known to modulate the immune system and to promote hematopoiesis. These dual effects make MSCs attractive for use as cellular therapy in hemato...

    Authors: Elizabeth O. Stenger, Lakshmanan Krishnamurti and Jacques Galipeau
    Citation: BMC Immunology 2015 16:74
  9. Macrophages are key players in the initiation, perpetuation and regulation of both innate and adaptive immune responses. They largely perform these roles through modulation of the expression of genes, especial...

    Authors: Akane Tanaka, Joyce To, Bronwyn O’Brien, Sheila Donnelly and Maria Lund
    Citation: BMC Immunology 2017 18:43
  10. Proinflammatory genes are highly expressed in several metabolic disorders associated with obesity. But it is not clarified whether gene expression levels and downstream inflammatory markers are related to the ...

    Authors: Parichehr Amiri, Behzad Baradaran, Maryam Saghafi-Asl, Mahsa Naghizadeh, Dariush Shanehbandi, Nahid Karamzad and Sepideh Zununi Vahed
    Citation: BMC Immunology 2019 20:23
  11. Cold stress, which may lead to local and systemic injury, is reported to be related to the immune system, especially the complement system. At present, the lack of effective treatment is a critical issue. Amen...

    Authors: Jiayi Cai, Chunyang Zhao, Yajie Du, Yuan Huang and Qingchun Zhao
    Citation: BMC Immunology 2019 20:49
  12. High-throughput sequencing of T cell receptor (TCR) genes is a powerful tool for analyses of antigen specificity, clonality and diversity of T lymphocytes. Here, we developed a new TCR repertoire analysis meth...

    Authors: Kazutaka Kitaura, Tadasu Shini, Takaji Matsutani and Ryuji Suzuki
    Citation: BMC Immunology 2016 17:38
  13. Active immunotherapy targeting amyloid-β (Aβ) is a promising treatment for Alzheimer’s disease (AD). Numerous preclinical studies and clinical trials demonstrated that a safe and effective AD vaccine should in...

    Authors: Ping Yang, Yongqing Guo, Yao Sun, Bin Yu, Haihong Zhang, Jiaxin Wu, Xianghui Yu, Hui Wu and Wei Kong
    Citation: BMC Immunology 2019 20:9
  14. Experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis, is induced by immunization of mice with myelin oligodendrocytic glycoprotein (MOG35-55) injections, and after 9 days, mice d...

    Authors: Patricia J McLaughlin, Daniel P McHugh, Marcus J Magister and Ian S Zagon
    Citation: BMC Immunology 2015 16:24
  15. T follicular helper (Tfh) cells play a control role in contribution of B cell differentiation and antibody production. T follicular regulatory (Tfr) cells inhibit Tfh-B cell interaction.

    Authors: Lin Yan, Yamei Li, Yi Li, Xiaojuan Wu, Xianding Wang, Lanlan Wang, Yunying Shi and Jiangtao Tang
    Citation: BMC Immunology 2019 20:26
  16. Gulf War Illness (GWI) is a clinically heterogeneous chronic condition that affects many veterans of the 1990–1991 Persian Gulf War. One of the most prevalent and debilitating symptoms of GWI is abnormal fatig...

    Authors: Luke Parkitny, Stephanie Middleton, Katharine Baker and Jarred Younger
    Citation: BMC Immunology 2015 16:57
  17. High-dose intravenous immunoglobulin (IVIg), and more recently, subcutaneously-delivered Ig (SCIg), are used to treat a variety of autoimmune diseases; however, there are challenges associated with product pro...

    Authors: Bonnie J. B. Lewis, Jade Ville, Megan Blacquiere, Selena Cen, Rolf Spirig, Adrian W. Zuercher, Fabian Käsermann and Donald R. Branch
    Citation: BMC Immunology 2019 20:44
  18. Delayed wound healing reduces the quality of life (QOL) of patients. Thus, understanding the mechanism of wound healing is indispensable for better management. However, the role of innate immunity in wound hea...

    Authors: Kazuhide Takada, Shihoko Komine-Aizawa, Naoko Hirohata, Quang Duy Trinh, Atsuyoshi Nishina, Hirokazu Kimura and Satoshi Hayakawa
    Citation: BMC Immunology 2017 18:19
  19. There is a growing body of evidences indicating iNOS has involved in the pathogenesis of SLE. However, the role of iNOS in SLE is inconsistency. This systematic review was designed to evaluate the association ...

    Authors: Lu Pan, Sirui Yang, Jinghua Wang, Meng Xu, Shaofeng Wang and Huanfa Yi
    Citation: BMC Immunology 2020 21:6
  20. Pentraxins are a family of highly conserved secreted proteins that regulate the innate immune system, including monocytes and macrophages. C-reactive protein (CRP) is a plasma protein whose levels can rise to ...

    Authors: Wensheng Chen, Darrell Pilling and Richard H. Gomer
    Citation: BMC Immunology 2017 18:47
  21. The lung is exposed to airborne fungal spores, and fungi that colonize the oral cavity such as Candida albicans, but does not develop disease to opportunistic fungal pathogens unless the immune system is compromi...

    Authors: Sabarirajan Jayaraja, Azzeddine Dakhama, Bogeon Yun, Moumita Ghosh, HeeJung Lee, Elizabeth F. Redente, Charis L. Uhlson, Robert C. Murphy and Christina C. Leslie
    Citation: BMC Immunology 2016 17:27
  22. We sought to compare Pneumovax®23 responses in adults with subnormal IgG subclass concentrations. We studied adults with normal total IgG, frequent/severe respiratory infection, and subnormal IgG1, IgG3, or Ig...

    Authors: Antony R. Parker, Markus Skold, Stephen Harding, J. Clayborn Barton, Luigi F. Bertoli and James C. Barton
    Citation: BMC Immunology 2019 20:29
  23. Technical feasibility of RNA quantification by real time RT-PCR has led to enormous utilization of this method. However, real time PCR results need to be normalized due to the high sensitivity of the method an...

    Authors: Mehdi Emam, Kathleen Thompson-Crispi and Bonnie Mallard
    Citation: BMC Immunology 2015 16:33
  24. The potency of T regulatory (TREG) cells to inhibit T helper (Th)-driven immune cell responses has been linked to increased intracellular cyclic-AMP (cAMP) levels of TREG cells. In an ovalbumin (OVA)-driven al...

    Authors: Kari J. Dugger, Taylor Chrisman, Sarah L. Sayner, Parker Chastain, Kacie Watson and Robert Estes
    Citation: BMC Immunology 2018 19:9
  25. Oxidative damage present in obese/overweight mothers may lead to further oxidative stress conditions or inflammation in maternal and cord blood samples. Thirty-four pregnant women/newborn pairs were included i...

    Authors: María Hernández-Trejo, Araceli Montoya-Estrada, Yessica Torres-Ramos, Aurora Espejel-Núñez, Alberto Guzmán-Grenfell, Rosa Morales-Hernández, Maricruz Tolentino-Dolores and Estibalitz Laresgoiti-Servitje
    Citation: BMC Immunology 2017 18:3
  26. Natural killer cell responses to virally-infected or transformed cells depend on the integration of signals received through inhibitory and activating natural killer cell receptors. Human Leukocyte Antigen nul...

    Authors: Alexandra Tremblay-McLean, Sita Coenraads, Zahra Kiani, Franck P. Dupuy and Nicole F. Bernard
    Citation: BMC Immunology 2019 20:8
  27. Mouse models have been extremely valuable in identifying the fundamental mechanisms of airway inflammation that underlie human allergic asthma. Several models are commonly used, employing different methods and...

    Authors: Evelyn J. Hyde, Kirsty A. Wakelin, Naomi J. Daniels, Sayani Ghosh and Franca Ronchese
    Citation: BMC Immunology 2019 20:18
  28. Requisites for an efficacious tuberculosis (TB) vaccine are a minimal genomic diversity among infectious Mycobacterium tuberculosis strains for the selected antigen, and the capability to induce robust T-cell res...

    Authors: Marie-Cécile Mortier, Erik Jongert, Pascal Mettens and Jean-Louis Ruelle
    Citation: BMC Immunology 2015 16:63
  29. There is now good evidence that cytokines and growth factors are key factors in tissue repair and often exert anti-infective activities. However, engineering such factors for global use, even in the most remot...

    Authors: Olivier Garraud, Wael N. Hozzein and Gamal Badr
    Citation: BMC Immunology 2017 18(Suppl 1):23

    This article is part of a Supplement: Volume 18 Supplement 1

  30. Bacterial genomes span a significant portion of diversity, reflecting their adaptation strategies; these strategies include nucleotide usage biases that affect chromosome configuration. Here, we explore an imm...

    Authors: Shireen Nigar, Yoshinari Yamamoto, Takuma Okajima, Suguru Shigemori, Takashi Sato, Tasuku Ogita and Takeshi Shimosato
    Citation: BMC Immunology 2017 18:44
  31. Abnormal immune function is often an underlying component of illness pathophysiology and symptom presentation. Functional and phenotypic immune-related alterations may play a role in the obscure pathomechanism...

    Authors: Sharni Lee Hardcastle, Ekua Weba Brenu, Samantha Johnston, Thao Nguyen, Teilah Huth, Naomi Wong, Sandra Ramos, Donald Staines and Sonya Marshall-Gradisnik
    Citation: BMC Immunology 2015 16:35
  32. Chronic eosinophilic pneumonia (CEP) or eosinophilic gastroenteritis (EG), or both, with asthma precede the onset of eosinophilic granulomatosis with polyangiitis (EGPA) in half of all EGPA patients. It is not...

    Authors: Naomi Tsurikisawa, Chiyako Oshikata, Takahiro Tsuburai, Satoshi Sugano, Yoko Nakamura, Takuya Shimoda, Shunpei Tamama, Ken Adachi, Ayako Horita, Ikuo Saito and Hiroshi Saito
    Citation: BMC Immunology 2015 16:75
  33. Monocytes and macrophages produce interleukin (IL)-10, an immunoregulatory cytokine and a potent therapeutic tool for immune disorders. Augmentation of IL-10 production with a concomitant reduction of proinfla...

    Authors: Masanori Inui, Kino Tazawa, Yoshiro Kishi and Toshiyuki Takai
    Citation: BMC Immunology 2015 16:20
  34. Fetuin-A/AHSH is a novel hepatokine that acts as a vascular calcification inhibitor and as an endogenous TLR-4 ligand. Fetuin-A may act as a positive or negative acute phase protein (APP) in disease conditions...

    Authors: Sardar Sindhu, Nadeem Akhter, Steve Shenouda, Ajit Wilson and Rasheed Ahmad
    Citation: BMC Immunology 2016 17:33
  35. C-reactive protein (CRP) exerts prothrombotic effects through dissociating from pentameric CRP (pCRP) into modified or monomeric CRP (mCRP). However, although the high prevalence of venous thromboembolism (VTE...

    Authors: Peng-cheng Xu, Shan Lin, Xiao-wei Yang, Dong-mei Gu, Tie-kun Yan, Li Wei and Bao-li Wang
    Citation: BMC Immunology 2015 16:10
  36. Systemic immune activation (inflammation) and immunosenescence develop in some people with advancing age. This process, known as “inflamm-aging,” is associated with physical frailty and sarcopenia. Meanwhile, ...

    Authors: Mark A. Wallet, Thomas W. Buford, Anna-Maria Joseph, Madhuri Sankuratri, Christiaan Leeuwenburgh, Marco Pahor, Todd Manini, John W. Sleasman and Maureen M. Goodenow
    Citation: BMC Immunology 2015 16:43
  37. Natural Killer (NK) cells are effector lymphocytes of the innate immune system and are subclassed into CD56BrightCD16Dim/− and CD56DimCD16+ NK cells. Intracellular calcium (Ca2+) is fundamental to regulate a numb...

    Authors: Cassandra Balinas, Helene Cabanas, Donald Staines and Sonya Marshall-Gradisnik
    Citation: BMC Immunology 2019 20:14
  38. Circulating bone marrow-derived monocytes can leave the blood, enter a tissue, and differentiate into M1 inflammatory, M2a remodeling/fibrotic, or M2c/Mreg resolving/immune-regulatory macrophages. Macrophages ...

    Authors: Darrell Pilling, Elkin Galvis-Carvajal, Tejas R. Karhadkar, Nehemiah Cox and Richard H. Gomer
    Citation: BMC Immunology 2017 18:30
  39. Immunologists often measure several correlated immunological markers, such as concentrations of different cytokines produced by different immune cells and/or measured under different conditions, to draw insigh...

    Authors: Bernd Genser, Joachim E. Fischer, Camila A. Figueiredo, Neuza Alcântara-Neves, Mauricio L. Barreto, Philip J. Cooper, Leila D. Amorim, Marcus D. Saemann, Thomas Weichhart and Laura C. Rodrigues
    Citation: BMC Immunology 2016 17:11
  40. Myeloid cells, especially mononuclear phagocytes, which include monocytes, macrophages and dendritic cells (DC), play vital roles in innate immunity, and in the initiation and maintenance of adaptive immunity....

    Authors: Hong Liu, Suryasarathi Dasgupta, Yu Fu, Brandi Bailey, Christian Roy, Eric Lightcap and Benjamin Faustin
    Citation: BMC Immunology 2019 20:42
  41. In genetically modified (GM) crops there is a risk that the inserted genes may introduce new allergens and/or adjuvants into the food and feed chain. The MON810 maize, expressing the insecticidal Cry1Ab toxin,...

    Authors: Monica Andreassen, Thomas Bøhn, Odd-Gunnar Wikmark, Johanna Bodin, Terje Traavik, Martinus Løvik and Unni Cecilie Nygaard
    Citation: BMC Immunology 2016 17:10
  42. Interleukin-15 is an immunostimulatory cytokine overexpressed in several autoimmune and inflammatory diseases such as Rheumatoid Arthritis, psoriasis and ulcerative colitis; thus, inhibition of IL-15-induced s...

    Authors: Yunier Rodríguez-Álvarez, Yanelys Morera-Díaz, Haydee Gerónimo-Pérez, Jorge Castro-Velazco, Rafael Martínez-Castillo, Pedro Puente-Pérez, Vladimir Besada-Pérez, Eugenio Hardy-Rando, Araceli Chico-Capote, Klaudia Martínez-Cordovez and Alicia Santos-Savio
    Citation: BMC Immunology 2016 17:30
  43. Cytokines, chemokines, adipocytokines, soluble cell receptors, and immune activation markers play an important role in immune responsiveness and can provide prognostic value since they reflect underlying condi...

    Authors: Najib Aziz, Roger Detels, Joshua J. Quint, David Gjertson, Timothy Ryner and Anthony W. Butch
    Citation: BMC Immunology 2019 20:33
  44. Potassium channel tetramerisation domain containing 9 (KCTD9), a member of KCTD family with a DNA-like pentapeptide repeat domain, was found to be increased particularly in NK cells of patients with HBV-induce...

    Authors: Xiaoping Zhang, Lin Zhu, Yaoyong Zhou, Aichao Shi, Hongwu Wang, Meifang Han, Xiaoyang Wan, Semvua Bukheti Kilonzo, Xiaoping Luo, Tao Chen and Qin Ning
    Citation: BMC Immunology 2018 19:20
  45. The saprophytic fungus Aspergillus fumigatus reproduces by generation of conidia, which are spread by airflow throughout nature. Since humans are inhaling certain amounts of spores every day, the (innate) immune ...

    Authors: Lothar Marischen, Anne Englert, Anna-Lena Schmitt, Hermann Einsele and Juergen Loeffler
    Citation: BMC Immunology 2018 19:39

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