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1070 result(s) for 'immunology' within BMC Immunology

Page 5 of 22

  1. Remission of multiple sclerosis during periods of high ovarian hormone secretion (such as pregnancy) has led to a great deal of interest in the potential for estrogens to treat autoimmune disease. Previous wor...

    Authors: Melissa A Yates, Yuexin Li, Peter J Chlebeck and Halina Offner
    Citation: BMC Immunology 2010 11:20
    Content type: Research article Published on:

  2. A major challenge in the application of marrow transplantation as a route to immunological tolerance of a transplanted organ is to achieve hematopoietic stem cell (HSC) engraftment with minimal myelosuppressiv...

    Authors: Luis Graca, Stephen Daley, Paul J Fairchild, Stephen P Cobbold and Herman Waldmann
    Citation: BMC Immunology 2006 7:9
    Content type: Research article Published on:

  3. Autoimmune lymphoproliferative syndrome (ALPS) is a rare inherited disorder characterized by defective function of Fas, autoimmune manifestations that predominantly involve blood cells, polyclonal accumulation...

    Authors: Elisa Cerutti, Maria F Campagnoli, Massimo Ferretti, Emanuela Garelli, Nicoletta Crescenzio, Angelo Rosolen, Annalisa Chiocchetti, Michael J Lenardo, Ugo Ramenghi and Umberto Dianzani
    Citation: BMC Immunology 2007 8:28
    Content type: Research article Published on:

  5. To understand the role of genetic factors on chromosome 1 in the regulation of spontaneous arthritis in mice deficient in IL-1 receptor antagonist protein (IL_1RA), we previously used speed congenic breeding t...

    Authors: Nan Deng, Yan Jiao, Yanhong Cao, Xiaoyun Liu, Yonghui Ma, Karen A Hasty, David D Brand, John M Stuart and Weikuan Gu
    Citation: BMC Immunology 2014 15:57
    Content type: Research article Published on:

  6. We have devised a simple and efficient fluorescence-based method to track antigen uptake and processing in human B lymphoblastoid cells (B-LCL). Fluorescein labelled subtilisin was used to optimize antigen upt...

    Authors: Namrata S Patil, David L Wong, Katherine D Collier and Hugh C McDonald
    Citation: BMC Immunology 2004 5:12
    Content type: Research article Published on:

  7. The use of new adjuvants in vaccine formulations is a subject of current research. Only few parenteral adjuvants have been licensed. We have developed a mucosal and parenteral adjuvant known as AFCo1 (Adjuvant...

    Authors: Caridad Zayas, Domingo González, Reinaldo Acevedo, Judith del Campo, Miriam Lastre, Elizabeth González, Belkis Romeu, Maribel Cuello, Julio Balboa, Osmir Cabrera, Luisa Guilherme and Oliver Pérez
    Citation: BMC Immunology 2013 14(Suppl 1):S4
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

  8. Inflammation is characterized by dynamic changes in the expression of cytokines, such as M-CSF, and modifications of lipids and proteins that result in the formation of ligands for Class A Scavenger Receptors ...

    Authors: Dejan Nikolic, Lindsay Calderon, Liqin Du and Steven R Post
    Citation: BMC Immunology 2011 12:37
    Content type: Research article Published on:

  9. Anti-glomerular basement membrane (GBM) disease is a well-known antibody-induced autoimmune disease. A few patients have glomerular C1q deposition, but it is usually absent on renal histopathology. The role of...

    Authors: Shui-yi Hu, Xiao-yu Jia, Xiao-wei Yang, Feng Yu, Zhao Cui and Ming-hui Zhao
    Citation: BMC Immunology 2013 14:42
    Content type: Research article Published on:

  10. CD8+ regulatory T cells (Treg) have been considered to be involved in a model of ocular-induced tolerance, known as anterior chamber-associated immune deviation (ACAID). The phenotype and characteristics of CD8+T...

    Authors: Hao He, Peizeng Yang, Liqiong Jiang, Junfeng Zhang, Changlin Zhao, Lina Chen, Xiaomin Lin, Hongyan Zhou and Aize Kijlstra
    Citation: BMC Immunology 2008 9:53
    Content type: Research article Published on:

  11. Oxidative stress plays a critical role on the processes of sepsis, and several microRNAs have been identified that may regulate the occurrence of oxidative stress. However, the relation between oxidative stres...

    Authors: Yingwei Ou, Rongcheng An, Haochu Wang, Lue Chen, Yong Shen, Wenwei Cai and Wei Zhu
    Citation: BMC Immunology 2022 23:14
    Content type: Research Published on:

  12. Alpha-fetoprotein (AFP) is a tumor-associated glycoprotein that functions in regulation of both ontogenic and oncogenic growth. Recent study showed that AFP can induce apoptosis or impair monocyte-derived dend...

    Authors: Agus Setiyono, Akterono D Budiyati, Sigit Purwantomo, Madonna R Anggelia, Ismail Fanany, Gunawan A Wibowo, Indra Bachtiar, Andi Utama and Susan Tai
    Citation: BMC Immunology 2011 12:4
    Content type: Research article Published on:

  13. Congenic strains of mice are assumed to differ only at a single gene or region of the genome. These mice have great importance in evaluating the function of genes. However, their utility depends on the mainten...

    Authors: Erin E McClelland, Kristy Damjanovich, Kyle Gardner, Zack J Groesbeck, Maggie S Ma, Megan Nibley, Kelly S Richardson, Maureen Wilkinson, Linda C Morrison, Paul Bernhardt and Wayne K Potts
    Citation: BMC Immunology 2004 5:14
    Content type: Research article Published on:

  15. TREM-1 (triggering receptor expressed on myeloid cells), a receptor expressed on neutrophils and monocytes, is upregulated in sepsis and seems to tune the inflammatory response. We explored the expression of T...

    Authors: Androniki Marioli, Marina Koupetori, Maria Raftogiannis, Maria Patrani, Nikolaos Antonakos, Maria Pavlaki, Georgios Adamis, Georgia Dougekou, Georgia Damoraki and Iraklis Tsangaris
    Citation: BMC Immunology 2014 15:585
    Content type: Research article Published on:

  16. We performed initial cell, cytokine and complement depletion studies to investigate the possible role of these effectors in response to vaccination with heat-killed Burkholderia mallei in a susceptible BALB/c mou...

    Authors: Gregory C Whitlock, Roman A Lukaszewski, Barbara M Judy, Slobodan Paessler, Alfredo G Torres and D Mark Estes
    Citation: BMC Immunology 2008 9:55
    Content type: Research article Published on:

  17. Patients with antibody deficiencies depend on the presence of a variety of antibody specificities in intravenous immunoglobulin (IVIG) to ensure continued protection against pathogens. Few studies have examine...

    Authors: Fernanda Aimée Nobre, Isabela Garrido da Silva Gonzalez, Raquel Maria Simão, Maria Isabel de Moraes Pinto and Beatriz Tavares Costa-Carvalho
    Citation: BMC Immunology 2014 15:26
    Content type: Research article Published on:

  18. Adult-onset Still's disease (AOSD) is a systemic inflammatory disease of unknown etiology, lacking specific diagnosis and disease activity evaluation indicators. This study will analyze the activity and clinic...

    Authors: Zhiye Xu, Linyu Geng, LiLi Guo, Hongyan Song, Jie Pan, Han Shen and Sen Wang
    Citation: BMC Immunology 2022 23:4
    Content type: Research Published on:

  19. Neutrophil migration to an inflamed site constitutes the first line of the innate immune response against invading microorganisms. Given the crucial role of endogenous lectins in neutrophil mobilization and ac...

    Authors: Selene Elifio-Esposito, Luciane Tomazeli, Carolina Schwartz, Ana Paula Gimenez, Gabriel M Fugii, Luiz Claudio Fernandes, Luciana FM Zishler, Patrícia M Stuelp-Campelo and Andréa N Moreno
    Citation: BMC Immunology 2011 12:10
    Content type: Research article Published on:

  20. Extracellular nucleotides (ATP, ADP, UTP and UDP) exert a wide range of biological effects in blood cells mediated by multiple ionotropic P2X receptors and G protein-coupled P2Y receptors. Although pharmacolog...

    Authors: Lingwei Wang, Sten Eirik W Jacobsen, Anders Bengtsson and David Erlinge
    Citation: BMC Immunology 2004 5:16
    Content type: Research article Published on:

  21. Bifidobacteria and lactobacilli are among the early and important colonizers of the gastrointestinal tract and are generally considered to be part of a normal, healthy microbiota. It is believed that specific ...

    Authors: David O'Mahony, Sharon Murphy, Thomas Boileau, JeanSoon Park, Frances O'Brien, David Groeger, Patrycja Konieczna, Mario Ziegler, Paul Scully, Fergus Shanahan, Barry Kiely and Liam O'Mahony
    Citation: BMC Immunology 2010 11:63
    Content type: Research article Published on:

  22. The P2X 7 receptor plays an important role in cytokine release during the inflammatory response in vivo. Polymorphisms within the P2X 7 ...

    Authors: Anke Wesselius, Martijn JL Bours, Ilja CW Arts, Esther HE Theunisz, Piet Geusens and Pieter C Dagnelie
    Citation: BMC Immunology 2012 13:64
    Content type: Research article Published on:

  23. Airway hyperresponsiveness (AHR) is one of the important traits that characterize bronchial asthma. Goishi tea is a post-heating fermented tea that has been reported to have higher free radical scavenging acti...

    Authors: Ryoji Hirota, Nlandu R Ngatu, Mitsuhiko Miyamura, Hiroyuki Nakamura and Narufumi Suganuma
    Citation: BMC Immunology 2011 12:45
    Content type: Research article Published on:

  24. The USDA, Wildlife Services cooperative oral rabies vaccination (ORV) program uses a live vaccinia virus-vectored (genus Orthopoxvirus) vaccine, Raboral V-RG® (V-RG), to vaccinate specific wildlife species agains...

    Authors: J Jeffrey Root, Robert G McLean, Dennis Slate, Kathleen A MacCarthy and Jorge E Osorio
    Citation: BMC Immunology 2008 9:57
    Content type: Research article Published on:

  26. Hemolytic uremic syndrome (HUS) leading to acute kidney failure, is a condition linked to the production of primarily Shiga toxin 2 (Stx2) by some E. coli serotypes. We have previously shown that Stx2 A subunit-s...

    Authors: Abhineet Sheoran, Kwang-il Jeong, Jean Mukherjee, Anthony Wiffin, Pradeep Singh and Saul Tzipori
    Citation: BMC Immunology 2012 13:27
    Content type: Research article Published on:

  29. Immunosuppression by gliomas contributes to tumor progression and treatment resistance. It is not known when immunosuppression occurs during tumor development but it likely involves cross-talk among tumor cell...

    Authors: Benjamin C Kennedy, Lisa M Maier, Randy D'Amico, Christopher E Mandigo, Elizabeth J Fontana, Allen Waziri, Marcela C Assanah, Peter Canoll, Richard CE Anderson, David E Anderson and Jeffrey N Bruce
    Citation: BMC Immunology 2009 10:11
    Content type: Research article Published on:

  30. Hemodialysis (HD) patients have an increased risk of acquiring infections due to many health care contacts and may, in addition, have a suboptimal response to vaccination and a high mortality from Covid-19 inf...

    Authors: Jan Melin, Maria K. Svensson, Bo Albinsson, Ola Winqvist and Karlis Pauksens
    Citation: BMC Immunology 2021 22:70
    Content type: Research article Published on:

  31. The immune response to trauma has traditionally been modeled to consist of the systemic inflammatory response syndrome (SIRS) followed by the compensatory anti-inflammatory response syndrome (CARS). We investi...

    Authors: Kevin R Kasten, Holly S Goetzman, Maria R Reid, Alison M Rasper, Samuel G Adediran, Chad T Robinson, Cindy M Cave, Joseph S Solomkin, Alex B Lentsch, Jay A Johannigman and Charles C Caldwell
    Citation: BMC Immunology 2010 11:4
    Content type: Research article Published on:

  32. Nonalcoholic fatty liver disease (NAFLD) has become the most common liver disease worldwide. Recent studies have shown that the Angptl2 pathway mediated hepatic inflammatory response plays an important role in...

    Authors: Zengsheng Lu, Beihui He, Zhiyun Chen, Maoxiang Yan and Liyan Wu
    Citation: BMC Immunology 2020 21:28
    Content type: Research article Published on:

  34. Immunization with the spike protein (S) of severe acute respiratory syndrome (SARS)-coronavirus (CoV) in mice is known to produce neutralizing antibodies and to prevent the infection caused by SARS-CoV. Polyet...

    Authors: Byoung-Shik Shim, Sung-Moo Park, Ji-Shan Quan, Dhananjay Jere, Hyuk Chu, Man Ki Song, Dong Wook Kim, Yong-Suk Jang, Moon-Sik Yang, Seung Hyun Han, Yong-Ho Park, Chong-Su Cho and Cheol-Heui Yun
    Citation: BMC Immunology 2010 11:65
    Content type: Research article Published on:

  35. IL-17+ T helper cells and Foxp3+ regulatory T cells are CD4+ T helper cells with reciprocally regulated differentiation and function. Their frequency and function vary in patients with chronic hepatitis B. In thi...

    Authors: Yinghua Niu, Hongli Liu, Donglin Yin, Ruitian Yi, Tianyan Chen, Hong'an Xue, Shulin Zhang, Shumei Lin and Yingren Zhao
    Citation: BMC Immunology 2011 12:47
    Content type: Research article Published on:

  36. Expression of murine CCL21 by dermal lymphatic endothelial cells (LEC) has been demonstrated to be one of the most important steps in Langerhans cell emigration from skin. Previously, our group and others have...

    Authors: Yanina Eberhard, Susana Ortiz, Alejandro Ruiz Lascano, Raquel Kuznitzky and Horacio Marcelo Serra
    Citation: BMC Immunology 2004 5:7
    Content type: Research article Published on:

  38. Mycobacterium tuberculosis (Mtb) infections are still a major cause of death among all infectious diseases. Although 99% of individuals infected with Mtb develop a CD4+ Th1 and CD8+ T cell mediated immunity as me...

    Authors: Marion Heuer, Anna-Sophie Behlich, Ji-Sook Lee, Eliana Ribechini, Eun-Kyeong Jo and Manfred B Lutz
    Citation: BMC Immunology 2013 14:48
    Content type: Research article Published on:

  39. Probiotics positively affect inflammatory responses, in part, through Janus kinase/signal transduction and activator of transcription (JAK/STAT) and inflammatory signaling pathways. To evaluate the precise eff...

    Authors: Shadi Aghamohammad, Amin Sepehr, Seyedeh Tina Miri, Saeideh Najafi, Mahdi Rohani and Mohammad R. Pourshafiea
    Citation: BMC Immunology 2022 23:8
    Content type: Research Published on:

  40. The new JAK3 inhibitor, CP690,550, has shown efficacy in the treatment of rheumatoid arthritis. The present study was undertaken to assess the effects of CP690,550 on cytokine production and cellular signaling...

    Authors: Kiyoshi Migita, Taiichiro Miyashita, Yasumori Izumi, Tomohiro Koga, Atsumasa Komori, Yumi Maeda, Yuka Jiuchi, Yoshihiro Aiba, Satoshi Yamasaki, Atsushi Kawakami, Minoru Nakamura and Hiromi Ishibashi
    Citation: BMC Immunology 2011 12:51
    Content type: Research article Published on:

  41. Ion channels are involved in the control of membrane potential (ψ) in a variety of cells. The maintenance of ψ in human T lymphocytes is essential for T-cell activation and was suggested to depend mostly on th...

    Authors: Fernanda Mello de Queiroz, Cristiano G Ponte, Adriana Bonomo, Rosane Vianna-Jorge and Guilherme Suarez-Kurtz
    Citation: BMC Immunology 2008 9:63
    Content type: Methodology article Published on:

  42. Tumor-associated dendritic cells (TADCs) can interact with tumor cells to suppress anti-tumor T cell immunity. However, there is no information on whether and how TADCs can modulate programmed death-ligand 1 (...

    Authors: Weigang Xiu and Jingjing Luo
    Citation: BMC Immunology 2021 22:3
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Immunology 2021 22:18

  43. Previous investigation has demonstrated that CD4+ T cells play a crucial role in effective immunity against Helicobacter pylori (H.pylori) infection. It has been well proved that Lpp20 is one of major protective ...

    Authors: Yan Li, Yin Jiang, Yue Xi, Lili Zhang, Jun Luo, Diandian He, Shuang Zeng and Yunshan Ning
    Citation: BMC Immunology 2012 13:68
    Content type: Research article Published on:

  44. CD72 is an inhibitory co-receptor expressed on B cells. We previously demonstrated significant association of the polymorphism of the CD72 gene with susceptibility to human systemic lupus erythematosus (SLE) in i...

    Authors: Yuki Hitomi, Takahiro Adachi, Naoyuki Tsuchiya, Zen-Ichiro Honda, Katsushi Tokunaga and Takeshi Tsubata
    Citation: BMC Immunology 2012 13:72
    Content type: Research article Published on:

  45. Cancer immunotherapy has gained increasing popularity as a novel approach to treat cancer. A member of the B7 family, V-domain immunoglobulin suppressor of T-cell activation (VISTA) is a novel immune checkpoin...

    Authors: Ting-ting Li, Jing-wei Jiang, Chen-xin Qie, Chun-xiao Xuan, Xin-lei Hu, Wan-mei Liu, Wen-ting Chen and Jun Liu
    Citation: BMC Immunology 2021 22:55
    Content type: Research article Published on:

  46. Pemphigus vulgaris (PV) is an acquired autoimmune blistering disorder in which greater than 80% of active patients produce autoantibodies to the desmosomal protein desmogelin 3 (Dsg3). As the disease progresse...

    Authors: Joo Chuan Tong and Animesh A Sinha
    Citation: BMC Immunology 2008 9:30
    Content type: Research article Published on:

  48. Despite high rate of vaccination coverage with 2-doses of measles containing vaccine among Iranian children, outbreaks of measles occurred among different age groups and fully vaccinated subjects. Although the...

    Authors: Hana Saffar, Sayed Jaber Mousavi, Hiva Saffar, Mohammad-Reza Parsaei, Gholam-Reza Ghorbani and Mohammad Jafar Saffar
    Citation: BMC Immunology 2022 23:2
    Content type: Research Published on:

  50. In celiac disease gluten, the disease-inducing toxic component in wheat, induces the secretion of autoantibodies which are targeted against transglutaminase 2 (TG2). These autoantibodies are produced in the sm...

    Authors: Satumarja M Stenman, Katri Lindfors, Ilma R Korponay-Szabo, Olli Lohi, Päivi Saavalainen, Jukka Partanen, Katri Haimila, Herbert Wieser, Markku Mäki and Katri Kaukinen
    Citation: BMC Immunology 2008 9:6
    Content type: Research article Published on:

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