BMC Immunology

Featured article: Fighting cancer with the immune system

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Studies have shown the immune system has the potential to remove tumor cells in a patient’s body. This article describes a method for generating antitumor cytotoxic T lymphocytes (CTLs) specific for the epitopes of the HER2/neu tumor-associated antigen. These CTLs are then shown to have a pronounced cytotoxic effect on tumor cells expressing the HER2/neu marker.

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Content type: Research article
| 14 September 2018

Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production

Authors: Li-Rong Lin, Wei Liu, Xiao-Zhen Zhu, Yu-Yan Chen, Zheng-Xiang Gao, Kun Gao, Man-Li Tong, Hui-Lin Zhang, Yao Xiao, Wen-Dong Li, Shu-Lian Li, Hui-Ling Lin, Li-Li Liu, Zan-Xi Fang, Jian-Jun Niu, Yong Lin…
Content type: Research article
| 3 August 2018

Pharmacologically upregulated carcinoembryonic antigen-expression enhances the cytolytic activity of genetically-modified chimeric antigen receptor NK-92MI against colorectal cancer cells

Authors: Masayuki Shiozawa, Chuan-Hsin Chang, Yi-Chun Huang, Yi-Ching Chen, Mau-Shin Chi, Hsu-Chao Hao, Yue-Cune Chang, Satoru Takeda, Kwan-Hwa Chi and Yu-Shan Wang
Content type: Research article
| 28 July 2018

The differences in immunoadjuvant mechanisms of TLR3 and TLR4 agonists on the level of antigen-presenting cells during immunization with recombinant adenovirus vector

Authors: Ekaterina Lebedeva, Alexander Bagaev, Alexey Pichugin, Marina Chulkina, Andrei Lysenko, Irina Tutykhina, Maxim Shmarov, Denis Logunov, Boris Naroditsky and Ravshan Ataullakhanov
Content type: Research article
| 28 July 2018

MiR-18a and miR-17 are positively correlated with circulating PD-1⁺ICOS⁺ follicular helper T cells after hepatitis B vaccination in a chinese population

Authors: Xiaojia Xu, Yulian Li, Yaping Liang, Mingjuan Yin, Zuwei Yu, Yan Zhang, Lingfeng Huang and Jindong Ni
Content type: Research article
| 11 July 2018

Sustained high glucose exposure sensitizes macrophage responses to cytokine stimuli but reduces their phagocytic activity

Authors: Sofia Pavlou, Jaime Lindsay, Rebecca Ingram, Heping Xu and Mei Chen

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Content type: Research article
| 5 February 2013

Characterization of murine macrophages from bone marrow, spleen and peritoneum

Authors: Changqi Wang, Xiao Yu, Qi Cao, Ya Wang, Guoping Zheng, Thian Kui Tan, Hong Zhao, Ye Zhao, Yiping Wang and David CH Harris
Content type: Research article
| 12 February 2013

Revisiting the white blood cell count: immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis - a prospective, observational study

Authors: Axel Nierhaus, Stefanie Klatte, Jo Linssen, Nina M Eismann, Dominic Wichmann, Jörg Hedke, Stephan A Braune and Stefan Kluge
Content type: Review
| 26 March 2015

Human helminth therapy to treat inflammatory disorders- where do we stand?

Authors: Helena Helmby
Content type: Research article
| 31 January 2015

Adoptive T-cell therapy of prostate cancer targeting the cancer stem cell antigen EpCAM

Authors: Zhenling Deng, Yanhong Wu, Wenbo Ma, Shuren Zhang and Yu-Qian Zhang
Content type: Research article
| 12 January 2007

Transcriptional profiling of the LPS induced NF-κB response in macrophages

Authors: Omar Sharif, Viacheslav N Bolshakov, Stephanie Raines, Peter Newham and Neil D Perkins

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Aims and scope

BMC Immunology is an open access journal publishing original peer-reviewed research articles in molecular, cellular, tissue-level, organismal, functional, and developmental aspects of the immune system as well as clinical studies and animal models of human diseases.

Editor

Linda Gummlich, BioMed Central

Section Editors

Simon R Carding, University of East Anglia
Lucienne Chatenoud, Hospital Necker
Olivier Garraud, Institut National de la Transfusion Sanguine
James Li, University of Hong Kong
J Philip McCoy, National Institutes of Health
Wayne Thomas, Institute for Child Health Research

Meet the Editors

Professor Wayne Thomas graduated with a PhD from the University of Western Australia in 1974. In 1984, he began a program at the Telethon Kids Institute in Western Australia to provide the structural data of house dust mite allergens. He joined the Editorial Board of BMC Immunology in 2012.

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Featured article: Fighting cancer with the immune system

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Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production

Pharmacologically upregulated carcinoembryonic antigen-expression enhances the cytolytic activity of genetically-modified chimeric antigen receptor NK-92MI against colorectal cancer cells

The differences in immunoadjuvant mechanisms of TLR3 and TLR4 agonists on the level of antigen-presenting cells during immunization with recombinant adenovirus vector

MiR-18a and miR-17 are positively correlated with circulating PD-1⁺ICOS⁺ follicular helper T cells after hepatitis B vaccination in a chinese population

Sustained high glucose exposure sensitizes macrophage responses to cytokine stimuli but reduces their phagocytic activity

Characterization of murine macrophages from bone marrow, spleen and peritoneum

Revisiting the white blood cell count: immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis - a prospective, observational study

Human helminth therapy to treat inflammatory disorders- where do we stand?

Adoptive T-cell therapy of prostate cancer targeting the cancer stem cell antigen EpCAM

Transcriptional profiling of the LPS induced NF-κB response in macrophages

Aims and scope

Editor

Section Editors

Meet the Editors

Research Data Support

BMC Series blog

Highlights of the BMC series: August 2018

Alcohol as part of ‘care practices’ in White British women’s everyday personal relationships

What do we know about migraine? Mechanisms, treatment and the future

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