Interferon-gamma coordinates CCL3-mediated neutrophil recruitment in vivo

Bonville, Cynthia A; Percopo, Caroline M; Dyer, Kimberly D; Gao, Jiliang; Prussin, Calman; Foster, Barbara; Rosenberg, Helene F; Domachowske, Joseph B

doi:10.1186/1471-2172-10-14

BMC Immunology

Table 1 Expression profiles that correlate with IFN-γ in PVM-infected mouse lung tissue.

From: Interferon-gamma coordinates CCL3-mediated neutrophil recruitment in vivo

Transcript	Symbol	Acc. No.	Correl.
Interferon-γ and related transcripts
Interferon-γ	Ifng	K00083	1.000
Interferon inducible protein 1	Ifi1	NM_008326	0.961
Interferon-stimulated protein	Isg20	BC022751	0.953
Interferon-γ induced GTPase	Igtp	NM_018738	0.953
Interferon-induced transmembrane protein 6	Ifitm6	BB193024	0.950
CXC chemokine ligand 11 (IP-9)	Cxcl11	NM_019494	0.949
Interferon inducible protein 47	Ifi47	NM_008330	0.940
Interferon activatible protein 203	Ifi203	AI607873	0.932
Interferon activated gene 205	Ifi205	AI481797	0.929
Interferon induced protein with tetratricopeptide repeats 1	Ifit1	NM_008331	0.929
Interferon consensus sequence binding protein 1	Icsbp1	BG069095	0.926
Interferon regulatory factor 7	Irf7	NM_016850	0.922
Interferon activated gene 205	Ifi205	AI481797	0.916
Interferon regulatory factor 5	Irf5	NM_012057	0.914
Interferon activated gene 203	Ifi203	NM_008328	0.910
Interferon-induced protein with tetratricopeptide repeats, 3	Ifit3	NM_010501	0.909
Interferon induced protein with tetratricopeptide repeats 2	Ifit2	NM_008332	0.901
Other inflammation-associated transcripts
CC Chemokine ligand 3 (MIP-1α)	Ccl3	NM_011337	0.965
Toll-like receptor 2	Tlr2	NM_011905	0.959
Interleukin-13 receptor alpha 1	Il13ra1	S80963	0.959
Suppressor of cytokine signaling 3	Socs3	NM_007707	0.951
Galectin-9	Lgals9	NM_010708	0.948
Interleukin-1 receptor antagonist	Il1rn	M57525	0.947
Regulator of G-protein signaling 19 interacting protein 1	Rgs19ip1	NM_018771	0.943
Interleukin-6	Il6	NM_031168	0.937
CD244 natural killer cell receptor 2B4	Cd244	NM_018729	0.928
CSF2 receptor	Csf2rb2	NM_007781	0.928
Fc receptor, IgG, high affinity, I	Fcgr1	AF143181	0.926
CC chemokine receptor 1	Ccr1	AV231648	0.926
Pentaxin-related gene	Ptx3	NM_008987	0.926
CXC chemokine ligand 13 (BLC)	Cxcl13	AF030636	0.921
CXC chemokine ligand 2 (MIP-2α)	Cxcl2	NM_009140	0.919
CXC chemokine ligand 5 (ENA-78)	Cxcl1	BB554288	0.914
Arginase II	Arg2	NM_009705	0.904
Signal transducer and activator of transcription 1	Stat1	AW214029	0.904
Regulator of G-protein signaling 1	Rgs1	NM_015811	0.903
CC chemokine receptor-like 2	Ccrl2	AJ318863	0.902
Various
Membrane-spanning 4-domains, subfamily A, member 8A	Ms4a8a	NM_022430	0.969
Chondroitin sulfate proteoglycan 2	Cspg2	BM251152	0.963
Fas death domain-associated protein	Daxx	NM_007829	0.960
O-acyltransferase domain containing 1	Oact1	AV366860	0.960
Mitogen activated protein kinase kinase kinase kinase 1	Map4k1	BB546619	0.960
Lymphocyte cytosolic protein 2	Lcp2	BC006948	0.959
Solute carrier family 15, member 3	Slc15a3	NM_023044	0.956
Indoleamine-pyrrole 2,3 dioxygenase	Indo	NM_008324	0.954
Proteosome subunit beta type 9	Tap1	AW048052	0.952
Phospholipase A1 member A	Pla1a	NM_134102	0.949
Methylene tetrahydrofolate dehydrogenase	Mthfd2	BG076333	0.949
Pre-B colony enhancing factor 1	Pbef1	AW989410	0.948
Thioredoxin reductase 1	Txnrd1	BB284199	0.948
CGG triplet repeat binding protein 1	Cggbp1	BI080272	0.945
Sphingosine kinase 1	Sphk1	AF068749	0.944
Pyrophosphatase	Pyp	NM_026438	0.944
2'-5' oligoadenylate synthetase 1G	Oas1g	BC018470	0.943
Ubiquitin D	Ubd	NM_023137	0.943
Apolipoprotein D	Apod	NM_007470	0.940
Membrane-spanning 4-domains, subfamily A, member 4C	Ms4a4b	NM_029499	0.936
AT rich interacting domain 5A	Arid5a	BC027152	0.935
Hemopoietic cell kinase	Hck	NM_010407	0.933
Histocompatibility 2, complement component factor B	H2-Bf	NM_008198	0.933
ATP binding cassette	Abcc5	BB436535	0.933
Cholesterol 25-hydroxylase	Ch25h	NM_009890	0.932
BING 4 protein	Bing4	C78559	0.932
Thymidylate kinase, LPS inducible	Tyki	AK004595	0.930
Tripartite motif protein 30	Trim30	BM240719	0.929
Tissue specific transplantation antigen 30	Tsta3	NM_031201	0.929
Syndecan binding protein	Sdcbp	AV227603	0.928
Prostaglandin-endoperoxide synthase 2	Ptgs2	M94967	0.926
Traf binding protein	T2bp	BB277065	0.925
Two pore segment channel 2	Tpcn2	BC025890	0.925
Early growth response 2	Egr2	X06746	0.925
GLI pathogenesis-related 2	Glipr2	BM208214	0.925
Cytochrome p450, family 7, subfamily b	Cyp7b1	NM_007825	0.924
Rab20, Ras oncogene	Rab20	BG066967	0.923
Solute carrier 39	Slc39a14	BB399837	0.922
Dual specificity phosphatase 3	Dusp3	BQ266434	0.922
Ribosome binding protein 1	Rrbp1	AF273691	0.922
Spermidine synthase	Srm	NM_009272	0.921
Ubiquitin-specific protease 18	Usp18	NM_011909	0.920
Lipocalin	Lcn2	X14607	0.920
Jun-B oncogene	Junb	NM_008416	0.919
Guanylate nucleotide binding protein 3	Gbp3	NM_018734	0.919
Pre-B cell colony-enhancing factor 1	Pbef1	AW989410	0.917
Membrane-spanning 4-domains subfamily A, member 6B	Ms4a6b	NM_027209	0.917
SLAM family member 7	Slamf7	AK016183	0.915
Ras and Rab interactor 1	Rin1	BC011277	0.915
Class II transactivator	C2ta	AF042158	0.913
Myxovirus resistance I	Mx1	M21039	0.910
Chloride channel calcium activated 2	Clca1	AF108501	0.910
Rap2C, member of RAS oncogene family	Rap2c	AK008416	0.910
Tumor necrosis factor, alpha induced protein 2	Tnfaip2	NM_009396	0.908
SLAM family member 8	Slamf8	BC024587	0.908

The microarray analysis software package, Genespring GX 7.3 'find similar' function was used to inspect all transcript profiles for patterns related to that displayed by IFN-γ. The minimum correlation considered to be similar was set at 0.900 (see Figure 1A).

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