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Table 1 The monoclonal antibodies used in the negative selection process.

From: Anti-idiotypic antibodies: a new approach in prion research

mAb

Form of mAb

Antigen used for mice immunization

Isotype

Specificity

Reference

E12/2

Fab

recBoPrP

IgG1

PrPC, PrPSc, α1-helix

[26]

C1/1

Fab

P1 (HuPrP: 214–226)

IgG1

PrPSc, PrPC

[23]

K4H5

Fab

P1 (HuPrP: 214–226)

IgG1

PrPSc

[23]

E9/5

IgG

P1 (HuPrP: 214–226)

IgG2a

PrPSc

[23]

  1. recBoPrP, recombinant bovine prion protein; HuPrP, human prion protein