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Figure 3 | BMC Immunology

Figure 3

From: Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice

Figure 3

Disease outcomes in arginase II-deficient mice. In A, cell composition of the BALF is shown. Data are from 3–4 mice per group. Representative experiment of 5 (2 with Aspergillus and 3 with OVA model) is shown. In B, airway hyperresponsiveness is shown. Data are from 4–6 mice per group. In C, collagen content of the lung is shown. Data are mean ± SD of 4–6 mice per group. In D, quantification of Ki67-positive cells by immunohistochemistry is shown. Data are from 2–5 mice/group. In B-D, two-way ANOVA demonstrated a statistically significant (P < 0.001) effect of treatment (allergen compared to saline), with no statistically significant effect of genotype or interaction (P > 0.05). In B-D, a representative experiment of two performed is shown.

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BMC Immunology

ISSN: 1471-2172

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