Ethanol inhibits NF-κB reporter construct activation by LPS in vivo. Transgenic mice with an NF-κB reporter driving expression of luciferase were imaged using an IVIS luminescence imager. Below each image of light emission profiles for the mice is a graph in which the data for those mice were analyzed using the IVIS software for integrated photon emission. Values shown are means ± SEM for the indicated group sizes. Values significantly different from the LPS control are indicated by ** (p < 0.01).