Figure 10

Role of CD18 and CD36 in OK-432 activation of MOs. MOs were incubated either with isotype control or anti-CD18/F(ab) (12.5 μg/ml) for 24 h (A). PBMCs were incubated either with isotype control or anti-CD36 (2.5 μg/ml) (B) prior to incubation with OK-432 for 24 h. Supernatants were analyzed for shown chemokines by Multiplex (MIP) or ELISA (MCP-1). A: n = 3; B: n = 6. CD18: MCP-1 (NS).