Table 3 Conservation of promiscuous epitopes
Epitope core | Protein | DRB1 alleles predicted to bind | Conservation |
|---|---|---|---|
VRAMSSLGS | PPE18 | 0101, 0401, 0404, 0405, 0802, 0901, 1101, 1301, 1501 | Unconserved |
MILIATNLL | PPE18 | 0101, 0401, 0404, 1301, 1302, 1501 | Unconserved |
MVSMANNHM | PPE18 | 0101, 0401, 0404, 0405, 1301, 1302 | Unconserved |
YVAWMSVTA | PPE18 | 0101, 0401, 0404, 0405, 1101 | Conserved |
LLGQNTPAI | PPE18 | 0101, 0401, 0404, 1301 | Conserved |
ILIATNLLG | PPE18 | 0101, 0401, 0404, 1301, 1501 | Unconserved |
ISNMVSMAN | PPE18 | 0101, 0401, 0404, 0405, 1101 | Unconserved |
LFSAASAFQ | PPE18 | 0101, 0401, 0405, 0901 | Conserved |
YVMPHSPAA | PPE18 | 0101, 0401, 0405, 0802 | Unconserved |
VSMTNTLSS | PPE18 | 0101, 0401, 0404, 0405 | Unconserved |
VVGMNTAAS | PepA | 0101, 0301, 0401, 0404, 0405, 0802, 1101, 1301, 1501 | Conserved |
VVLTNNHVI | PepA | 0101, 0405, 0701, 0802, 1101, 1301, 1302, 1501 | Conserved |
VVGSAPAAS | PepA | 0101, 0404, 0802, 0901, 1101, 1301 | Conserved |
FLGLGVVDN | PepA | 0101, 0401, 0405, 1101 | Conserved |
LRGAGGLPS | PepA | 0101, 0802, 1101, 1301 | Conserved |