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Figure 1 | BMC Immunology

Figure 1

From: Site-directed mutagenesis reveals a unique requirement for tyrosine residues in IL-7Rα and TSLPR cytoplasmic domains in TSLP-dependent cell proliferation

Figure 1

Conservation of cytoplasmic tyrosine residues in IL-7Rα/TSLPR across species. Sequence alignments of (A) the IL-7Rα cytoplasmic domains from Mus musculus, Rattus norvegicus, Homo sapiens, Pan troglodytes, Macaca mulatta, Canis lupus familiaris, Bos taurus, and Gallus gallus and (B) the TSLPR cytoplasmic domains from Homo sapiens, Canis lupus familiaris, Bos taurus, Mus musculus, and Rattus norvegicus were performed using ClustalX version 2.0.10 with the BLOSUM62 matrix. The conserved amino acid residues are highlighted in yellow while tyrosine residues are in red; conserved tyrosine residues are indicated by a red arrow.

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BMC Immunology

ISSN: 1471-2172

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