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Figure 7 | BMC Immunology

Figure 7

From: Phenotype, functions and fate of adoptively transferred tumor draining lymphocytes activated ex vivo in mice with an aggressive weakly immunogenic mammary carcinoma

Figure 7

Adoptively transferred B/I-activated cells proliferate in vivo. Mice with established 4T1 flank tumors were treated with CYP on day 9 after tumor inoculation followed by AIT with 50 × 106 CFSE-stained B/I activated lymphocytes from culture (on day 10). At 3 days after AIT, the tDLN, and contralateral LN (cLN) were harvested and analyzed by flow cytometry for CFSE+ cells. Proliferation and generations of CFSE+ cells were analyzed with ModFit software. Modfit analysis showed the presence of at least 9 cell generations (Reduced chi-squared = 1.238)

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BMC Immunology

ISSN: 1471-2172

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