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Table 1 Comparison of the phenotypic characteristic of MDDC at three stages dependent on treatments

From: Immunoregulatory effects of AFP domains on monocyte-derived dendritic cell function

   Surface Marker Expression (%)
   CD14+ HLA-DRhigh CD80+ CD40+ CD83+
    /CD11chigh /CD86high   
  Monocytes* 91.03 ± 0.75 42.70 ± 2.04 0.03 ± 0.03 22.83 ± 9.92 2.20 ± 0.70
Non Treated imMDDC 5.80 ± 2.91 67.47 ± 3.94 1.33 ± 0.10 52.47 ± 14.98 15.83 ± 6.70
  mMDDC 5.17 ± 0.82 91.4 ± 3.12 92.57 ± 1.52 96.30 ± 0.75 80.97 ± 2.28
FL-AFP imMDDC 1.30 ± 0.60 47.73 ± 4.45 2.47 ± 0.43 38.50 ± 7.30 10.33 ± 2.68
  mMDDC 1.47 ± 0.57 53.70 ± 3.94** 17.67 ± 2.35** 65.57 ± 0.30** 27.17 ± 3.94**
D1-AFP imMDDC 2.40 ± 1.47 56.27 ± 2.50 3.50 ± 0.79 54.80 ± 11.47 12.30 ± 2.10
  mMDDC 1.87 ± 0.38 73.63 ± 4.76 65.47 ± 7.03 90.07 ± 3.66 59.27 ± 8.90
D2-AFP imMDDC 1.07 ± 0.17 44.30 ± 2.04 6.37 ± 1.09 63.53 ± 10.02 17.10 ± 3.65
  mMDDC 2.40 ± 0.40 41.57 ± 6.20** 28.20 ± 4.59** 87.63 ± 5.51 34.70 ± 3.43**
D3-AFP imMDDC 1.90 ± 0.53 48.27 ± 2.28 6.90 ± 1.65 66.30 ± 9.89 21.97 ± 5.88
  mMDDC 2.07 ± 0.09 43.80 ± 6.91** 27.47 ± 4.06** 85.27 ± 4.89 39.27 ± 6.21**
  1. * ImMDDC is immature MDDC. mMDDC is mature MDDC. Generation of each cell is described in the "Methods".
  2. **showed significant differences compare to non-treated (Tukey test, p < 0.05)