Figure 3
From: Inhibitory effects of the JAK inhibitor CP690,550 on human CD4+ T lymphocyte cytokine production
Effects of CP690, 550 on cytokine genes expression in Con-A activated CD4+ T cells. CD4+ T cells were stimulated with concanavalin A in the presence or absence of CP690,550. After 24-hr stimulation, total RNA was extracted and IL-2, IFN-γ, IL-4, IL-17A and IL-22 mRNA expression was measured by real-time PCR. The results show a representative result from three independent experiments.