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Figure 3 | BMC Immunology

Figure 3

From: RAGE and ICAM-1 differentially control leukocyte recruitment during acute inflammation in a stimulus-dependent manner

Figure 3

Leukocyte adhesion in TNF-α-stimulated cremaster muscle venules during additional fMLP superfusion. Leukocytes adhesion (number of adherent cells/mm2) was observed in 3 h TNF-α-stimulated cremaster muscle venules of wild type (WT) control mice (6 venules in 6 mice), RAGE-/- mice (5 venules in 5 mice) and Icam1-/- mice (4 venules in 4 mice) before and during 5 minutes fMLP-superfusion (10 μM). All values are presented as mean ± SEM and significant differences (p < 0.05) vs. WT control mice are indicated by the asterisk.

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