Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension

Table 1 Summary of PAH scores of B6, BALB, and transgenic strains of mice

Mice*		n†	Median of score	95% CI‡	Statistics§
B6		9	0	0 - 0.1
BALB		2	0	n.d.
B6. TgL		15	0.7	0.35 - 1.05	¶
BALB. TgL		8	0	0 - 0.1
BCF1. TgL		30	0.05	0 - 0.1
BCN2. TgL	female	174	0.25	0.2 - 0.4	¶
BCN2. TgL	male	167	0.25	0.2 - 0.4	¶

* All mice were killed at 20 week-old for this examination. BCF1, BALB × B6; BCN2, BCF1 × B6.TgL.
† Number of mice tested.
‡ CI, confidential interval. The CI was not determined (n.d.) for BALB/c (BALB).
§ The significance of this study was evaluated by Mann-Whitney U-test for the all strains.
¶, P < 0.01 (v.s. B6).

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