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Table 1 Gene expression profile of cytokines and their receptors in the odontoblast layer (ODL) and pulp of normal teeth*.

From: Caries induced cytokine network in the odontoblast layer of human teeth

ODL > PULP PULP > ODL
BCL6, CEBPB, ICEBERG, IL1R1, IL5RA, IL8, MIF, SPP1, TOLLIP C3, CCL16, CCL19, CCL2, CCL21, CCL23, CCL25, CCL4, CCL5, CCL8, CCR2, CCR3, CCR5, CX3CR1, CXCL1, CXCL12, CXCL14, CXCL2, CXCL5, IL5, IL9, LTB4R, TNFA, CD40LG, XCR1
  1. Abbreviations: BCL6, B-cell CLL/lymphoma 6; CEBPB, Enhancer binding protein beta; ICEBERG, ICEBERG caspase-1 inhibitor; IL1R1, Interleukin 1 receptor, type I; IL5RA, interleukin 5 receptor alpha; IL8, Interleukin 8; MIF, Macrophage migration inhibitory factor; SPP1, Secreted phosphoprotein 1 (osteopontin, bone sialoprotein I); TOLLIP, Toll-interacting protein; C3, complement component 3; CCL16, Chemokine (C-C motif) ligand 16; CCR2, Chemokine (C-C motif) receptor 2; CX3CR1, Chemokine (C-X3-C motif) receptor 1; CXCL1, Chemokine (C-X-C motif) ligand 1; LTB4R, Leukotriene B4 receptor; TNFA, Tumor necrosis factor alpha; CD40LG, CD40 ligand; XCR1, Chemokine (C motif) receptor 1; XCR1, chemokine (C motif) receptor 1.
  2. *These data were obtained from PCR arrays and qPCR verification of cDNA array data including CCR2, CCR4, CCR5, CCR9, CCL3, CCL23, IL1B, TNFA, LTA, IL1R1, MIF, CXCL12, and CXCL14.