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Figure 1 | BMC Immunology

Figure 1

From: The P2X7 loss-of-function Glu496Ala polymorphism affects ex vivo cytokine release and protects against the cytotoxic effects of high ATP-levels

Figure 1

Cytokine and LDH release A-E LPS/PHA-induced cytokine release in response to 24 h stimulation by ATP at different concentrations (0.3, 0.9 and 3 mM), in subjects without the Glu496Ala P2X 7 receptor polymorphism (P2X7WT) vs. subjects with this SNP (P2X7MUT). Results are expressed as percent change from baseline (LPS/PHA-stimulation without ATP incubation) ± SEM. E LDH release in response to ATP stimulation in subjects without the Glu496Ala P2X7 receptor polymorphism (P2X7WT) vs. subjects with this SNP (P2X7MUT) * Significant difference between P2X7MUT and P2X7WT (p < 0.05).

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BMC Immunology

ISSN: 1471-2172

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