|
Seroprotection rate pre-vaccination (day 1)
|
|
H3N2
|
13 (65)
|
12 (60)
|
0.744
|
|
H1N1
|
4 (20)
|
5 (25)
|
0.705
|
|
B
|
16 (80)
|
17 (85)
|
0.677
|
|
H3N2, H1N1, and B
|
2 (10)
|
4 (20)
|
0.376
|
|
Seroprotection rate post-vaccination (day 22)
|
|
H3N2
|
18 (90)
|
20 (100)
|
0.147
|
|
H1N1
|
18 (90)
|
18 (90)
|
1.000
|
|
B
|
18 (90)
|
20 (100)
|
0.147
|
|
H3N2, H1N1, and B
|
15 (75)
|
18 (90)
|
0.212
|
|
Seroresponse rate post-vaccination (day 1 to 22)
|
|
H3N2
|
10 (50)
|
12 (60)
|
0.525
|
|
H1N1
|
13 (65)
|
12 (60)
|
0.744
|
|
B
|
2 (10)
|
3 (15)
|
0.633
|
|
H3N2, H1N1, and B
|
1 (5)
|
2 (10)
|
0.548
|
|
IL-10 production at baseline (day 1, pg/ml)
|
|
H3N2
|
4.5±10.9
|
2.5±5.0
|
0.457
|
|
H1N1
|
65.6±127.4
|
35.3±47.2
|
0.329
|
|
B
|
19.3±56.0
|
10.5±20.2
|
0.514
|
|
Treg at baseline (day 1, %)
|
|
Unstimulated
|
2.8±1.2
|
2.7±1.5
|
0.733
|
|
IFN-γ production post-vaccination (day 8, pg/ml)
|
|
H3N2
|
162.1±220.5
|
116.0±180.8
|
0.474
|
|
H1N1
|
578.3±828.8
|
382.5±446.1
|
0.360
|
|
B
|
316.4±520.7
|
418.1±528.9
|
0.544
|
|
IL-4 production post-vaccination (day 8, pg/ml)
|
|
H3N2
|
0.0±0.0
|
4.3±13.5
|
0.169
|
|
H1N1
|
0.0±0.0
|
7.7±20.2
|
0.105
|
|
B
|
2.9±8.8
|
0.0±0.0
|
0.163
|
|
IL-5 production post-vaccination (day 8, pg/ml)
|
|
H3N2
|
1.4±4.3
|
1.7±4.7
|
0.811
|
|
H1N1
|
1.2±3.4
|
1.5±4.5
|
0.788
|
|
B
|
0.8±3.4
|
3.4±6.4
|
0.114
|
