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Table 2 Humoral and cellular immune responses

From: Humoral and cellular immune responses after influenza vaccination in patients with chronic fatigue syndrome

  Chronic fatigue syndrome patients (n=20) Healthy controls (n=20) p-value
Seroprotection rate pre-vaccination (day 1)
 H3N2 13 (65) 12 (60) 0.744
 H1N1 4 (20) 5 (25) 0.705
 B 16 (80) 17 (85) 0.677
 H3N2, H1N1, and B 2 (10) 4 (20) 0.376
Seroprotection rate post-vaccination (day 22)
 H3N2 18 (90) 20 (100) 0.147
 H1N1 18 (90) 18 (90) 1.000
 B 18 (90) 20 (100) 0.147
 H3N2, H1N1, and B 15 (75) 18 (90) 0.212
Seroresponse rate post-vaccination (day 1 to 22)
 H3N2 10 (50) 12 (60) 0.525
 H1N1 13 (65) 12 (60) 0.744
 B 2 (10) 3 (15) 0.633
 H3N2, H1N1, and B 1 (5) 2 (10) 0.548
IL-10 production at baseline (day 1, pg/ml)
 H3N2 4.5±10.9 2.5±5.0 0.457
 H1N1 65.6±127.4 35.3±47.2 0.329
 B 19.3±56.0 10.5±20.2 0.514
Treg at baseline (day 1, %)
 Unstimulated 2.8±1.2 2.7±1.5 0.733
IFN-γ production post-vaccination (day 8, pg/ml)
 H3N2 162.1±220.5 116.0±180.8 0.474
 H1N1 578.3±828.8 382.5±446.1 0.360
 B 316.4±520.7 418.1±528.9 0.544
IL-4 production post-vaccination (day 8, pg/ml)
 H3N2 0.0±0.0 4.3±13.5 0.169
 H1N1 0.0±0.0 7.7±20.2 0.105
 B 2.9±8.8 0.0±0.0 0.163
IL-5 production post-vaccination (day 8, pg/ml)
 H3N2 1.4±4.3 1.7±4.7 0.811
 H1N1 1.2±3.4 1.5±4.5 0.788
 B 0.8±3.4 3.4±6.4 0.114
  1. Data are presented as absolute numbers with percentages in brackets or as mean ± standard error of the mean.