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Table 2 Multivariate analysis of factors affecting levels of soluble IL-7 receptors (sIL7R) at different time points after HSCT

From: Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults

Factor

RH

95% CI

p-value

1 month after HSCT

 

Sibling donor

1.23

0.95–1.61

0.13

aGVHD

0.76

0.58–0.99

< 0.05

2 months after HSCT

 

Sibling donor

1.31

1.01–1.70

< 0.05

CMV infection

0.83

0.64–1.08

0.17

aGVHD

0.70

0.55–0.90

< 0.01

3 months after HSCT

 

Sibling donor

2.23

1.34–3.71

0.004

aGVHD

0.91

0.70–1.20

0.50

ATG

1.66

0.99–2.78

0.06

6 months after HSCT

 

Sibling donor

1.86

1.21–2.86

< 0.01

aGVHD

0.77

0.58–1.04

0.09

ATG

1.30

0.83–2.04

0.26

12 months after HSCT

 

Sibling donor

1.30

0.97–1.74

0.09

HLA-Mismatch

2.12

1.59–2.82

< 0.001

  1. Abbreviations: RH relative hazard, CI confidence interval, aGVHD acute graft-versus-host disease, ATG anti-thymocyte globulin, CMV cytomegalovirus.