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Figure 1 | BMC Immunology

Figure 1

From: Exogenous interleukin-10 alleviates allergic inflammation but inhibits local interleukin-10 expression in a mouse allergic rhinitis model

Figure 1

rmIL-10 reduced the infiltration of eosinophils and mast cells in nasal mucosa. Representative photomicrographs (original magnification × 400) of nasal mucosa sections of mice stained with haematoxylin and eosin (H&E) for eosinophils (black arrows) or by mast cell staining for mast cells (white arrows) (A). A significantly increased number of eosinophils (B) and mast cells (C) in the lamina propria (LP) were observed in the AR group compared with the control group, and such increase was obviously alleviated by rmIL-10 treatment in the IL-10 group. Control group, saline-sensitized and challenged mice; AR group, ovalbumin-sensitized and challenged mice; IL-10 group, AR mice were treated with rmIL-10 during challenge.

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