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Figure 2 | BMC Immunology

Figure 2

From: Exogenous interleukin-10 alleviates allergic inflammation but inhibits local interleukin-10 expression in a mouse allergic rhinitis model

Figure 2

rmIL-10 administration increased total IL-10 levels but decreased other cytokine levels in NLF. Cytokine levels in nasal lavage fluid (NLF) were assessed by means of ELISA. Compared with the control group, the levels of all cytokines in the NLF were significantly elevated in AR group, and rmIL-10 administration during challenge markedly reduced the levels of IFN-γ, IL-5, IL-17, and TGF-β1 (A-B and D-E), but further increased the IL-10 levels (C). Control group, saline-sensitized and challenged mice; AR group, ovalbumin-sensitized and challenged mice; IL-10 group, AR mice were treated with rmIL-10.

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