Figure 13

KRC/ZAS-N site selection consensus motif search: MAST results Human and murine genomic DNA identified by MAST by searching with the KRC/ZAS-N are listed. Features of DNA sequence from GenBank/NCBI are delineated by bar and footnote as follows: a. H. Sapiens COL4A6 gene, nt 16–60: COL4A6 exon 15 b. H. Sapiens IgH gene primer, DJ segment, 7–27: leukemia-specific primer c. H. Sapiens IgH gene primer, DJ segment, 30–46: D segment (Dxp1) d. H. Sapiens IgH gene primer, DJ segment, 47–59: J segment (J5) e. M. Musculus DNA for desmin-binding fragment DesF7, 1–107: LINE element The first line describes the GenBank-designated name of the DNA sequence. The next line lists the accession number and any publications associated with the sequence. The third line indicates the target sequence nucleotide positions of overlap as well as orientation. The combined p-value is defined as the probability of a randomly generated sequence of the same length having sequence p-values whose product is at least as small as the product of the sequence p-values of the matches of the motifs to the given sequence. The E-value of the match of a sequence in a database to a group of motifs is defined as the expected number of sequences in a random database of the same size that would match the motifs as well as the sequence does and is equal to the combined p-value of the sequence times the number of sequences in the database. (Above is described in detail at MAST http://www.sdsc.edu/mast[34]).