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Figure 2 | BMC Immunology

Figure 2

From: Stage-specific changes in fetal thymocyte proliferation during the CD4-8- to CD4+8+ transition in wild type, Rag1-/-, and Hoxa3,Pax1 mutant mice

Figure 2

Proliferation of E17.5 Hoxa3-Pax1 compound mutant thymocytes compared to wild type. Panels A-B show CD44 vs. CD25 dot plots of the gated CD3-4-8- population from E17.5 wild type (A) and Hoxa3+/-Pax1-/- (B) thymus. Percentages are shown in each quadrant. C. Percentages of BrdU+ cells (Mean ± SEM) in each of 4 subsets of TN cells defined by CD44 and CD25, and in DP cells. D, E. CD44 vs. CD25 dot plots of the gated CD3-4-8- population divided into five subsets as defined by [12]. F. Percentages of BrdU+ cells (Mean ± SEM) in each of 3 CD44- TN subsets defined in panels D and E. DP values shown for comparison are the same as in C.

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BMC Immunology

ISSN: 1471-2172

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