Skip to main content

Advertisement

Table 1 Surface molecule expression on peritoneal macrophages from silicone injected rats.

From: Activation of macrophages by silicones: phenotype and production of oxidant metabolites

  CD54 CD44 CD11b/c CD80 CD86
Groups Positive (%) MFI Positive (%) MFI Positive (%) MFI Positive (%) MFI Positive (%) MFI
Normal 98 ± 1 39 ± 3 99 ± 1 146 ± 6 99 ± 1 328 ± 20 75 ± 1 6 ± 1 16 ± 5 2 ± 1
24 h 98 ± 1 57 ± 6 a 100 ± 1 200 ± 15 a 80 ± 1 c 66 ± 12 c 39 ± 1 b 6 ± 1 18 ± 2 4 ± 1 a
48 h 93 ± 2 52 ± 2 a 100 ± 1 202 ± 8 a 84 ± 1 c 70 ± 6 c 27 ± 4 b 5 ± 1 14 ± 1 4 ± 1 a
45 days 99 ± 1 52 ± 6 a 100 ± 1 209 ± 27 a 100 ± 1 404 ± 40 a 76 ± 11 6 ± 1 44 ± 6 b 3 ± 1 a
  1. The mean ± SEM of a least 4 rats is given. MFI, mean fluorescence intensity. Significant differences vs. normal controls are underlined. aP < 0.05, b p < 0.01,c p < 0.001