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Figure 2 | BMC Immunology

Figure 2

From: Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus

Figure 2

Peptide specific IgG1 and IgG2a antibodies in NOD mice immunized with G7 (A), PD (B), or HEL/OVA (C) peptides. Serum was collected 2–3 days before challenge with G7, PD, HEL/OVA or saline. IgG1 and IgG2a antibody responses specific for the G7, PD or HEL/OVA peptide epitopes were analyzed by ELISA. Each mouse was tested individually at a serum dilution of 1:20,000 for IgG1, and 1:25 for IgG2a for mice immunized against G7 peptides and 1:500 for IgG1 and 1:200 for IgG2a for mice immunized against PD or HEL/OVA peptides. Data are shown as mean +/- s. e. m. "Saline" = mice injected with saline/IFA; none = non-injected naïve mice.

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BMC Immunology

ISSN: 1471-2172

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