Median histamine-release, expressed as absolute amount (ng/ml blood) or as histamine-releasability (% of total cellular histamine content of the blood) from each S. mansoni-infected individual, induced by in vitro stimulation with either anti-IgE, SEA or SWA, pre-treatment, 1-day or 21-days post-treatment. Numbers in brackets are 25% and 75% percentiles, respectively. Differences in absolute amounts between pre-treatment and either post-treatment time-points are statistically significant (p < 0.05). Differences in absolute amounts between SEA-stimulated and anti-IgE-stimulated histamine-release and between SWA-stimulated and anti-IgE-stimulated histamine-release are statistically significant (p < 0.05) at all time-points. The difference in absolute amounts between SEA-stimulated and SWA-stimulated histamine-release is statistically significant(p < 0.05) at 21-days post-treatment. Statistically significant differences in histamine-releasability are mentioned in the text. (Wilcoxon's ranks tests).