Table 1 Immune-response related genes which were found to be significantly up-regulated in PBMCs of SARS patients. Level of expression is expressed in Fold change (average of fold changes of ten patients, S1-S10) as compared to that of control samples from normal human subjects (C1-C4).
From: Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome
Gen Bank ID | Description | Gene name | Fold change (S1-S10) |
|---|---|---|---|
NM_002343.1 | Lactotransferrin | LTF | 149.63 |
M33326.1 | Carcinoembryonic antigen-related cell adhesion molecule 8 | CEACAM8 | 97.29 |
NM_005564.1 | Lipocalin 2 | LCN2 | 80.40 |
NM_004660.2 | S100 calcium binding protein A9 | S100A9 | 65.39 |
NM_001725.1 | Bactericidal permeability-increasing protein | BPI | 49.94 |
NM_005091.1 | Peptidoglycan recognition protein | PGLYRP | 47.86 |
NM_001925.1 | Defensin alpha 4 | DEFA4 | 46.88 |
U19970.1 | Antimicrobial LPS-binding protein CAP18 | CAMP | 43.36 |
NM_005980.1 | S100 calcium-binding protein P | S100P | 39.52 |
NM_005143.1 | Haptoglobin | HP | 34.78 |
NM_004084.2 | Defensin alpha 1 | DEFA1 | 29.51 |
NM_006865.1 | Leukocyte immunoglobulin-like receptor, subfamily A, member 3 | LILRA3 | 19.43 |
NM_002870.1 | RAS oncogene family (RAB13) | RAB13 | 14.85 |
NM_003064.1 | Secretory leukocyte protease inhibitor | SLPI | 11.35 |
NM_000265.1 | Neutrophil cytosolic factor 1 | NCF1 | 11.30 |
NM_000634.1 | Interleukin 8 receptor alpha | IL8RA | 10.85 |
AL138717 | Rag D protein | RAGD | 7.84 |
BG327863 | CD24 antigen | CD24 | 7.69 |
NM_000419.2 | integrin, alpha 2b (antigen CD41B) | ITGA2B | 5.50 |
NM_001828.3 | Charot-Leyden crystal protein | CLC | 5.47 |
AI078167 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | NFKBIA | 5.21 |
NM_005621.1 | S100 calcium-binding protein A12 | S100A12 | 5.05 |
NM_003255.2 | Tissue inhibitor of metalloproteinase 2 | TIMP2 | 4.93 |
NM_002029.1 | Formyl peptide receptor 1 | FPR1 | 4.59 |
NM_005384.1 | Nuclear factor, interleukin 3 regulated | NFIL3 | 4.50 |
M25915.1 | Complement cytolysis inhibitor (CLI) | CLU | 4.07 |
NM_002965.2 | S100 calcium-binding protein A9 | S100A9 | 4.05 |
NM_014214.1 | Inositol (myo)-1(or 4)-monophosphatase 2 | IMPA2 | 3.95 |
NM_003189.1 | T-cell acute lymphocytic leukemia 1 | TAL1 | 3.94 |
U62027.1 | C3a receptor | C3AR1 | 3.83 |
NM_001150 | Alanyl (membrane) aminopeptidase | ANPEP | 3.83 |
BE789881 | RAS oncogene family | RAB31 | 3.75 |
NM_001769.1 | CD9 antigen (p24) | CD9 | 3.73 |
NM_014358.1 | C-type lectin, superfamily member 9 | CLECSF9 | 3.53 |
NM_006834.1 | RAS oncogene family member (RAB32) | RAB32 | 3.40 |
J04162.1 | Leukocyte IgG receptor (Fc-gamma-R) | FCGR3A | 3.32 |
NM_006866.1 | Lleukocyte immunoglobulin-like receptor, subfamily A2 | LILRA2 | 3.30 |
U41070.1 | Leukotriene b4 receptor | LTB4R | 3.23 |
NM_000632.2 | Integrin, alpha M | ITGAM | 3.20 |
BC003393.1 | Phosphoinositide-3-kinase, catalytic, beta polypeptide | PIK3CB | 3.13 |
NM_002432.1 | Myeloid cell nuclear differentiation antigen | MNDA | 3.08 |
NM_003264.1 | Toll-like receptor 2 | TLR2 | 3.05 |
NM_004475.1 | Flotillin 2 | FLOT2 | 3.04 |
NM_003461.1 | Zyxin | ZYX | 2.96 |
NM_003897.1 | Immediate early response 3 | IER3 | 2.91 |
AF119873.1 | Serine (or cysteine) proteinase inhibitor alpha-1 | SERPINA1 | 2.87 |
NM_016205.1 | Platelet derived growth factor C | PDGFC | 2.74 |
NM_005479.1 | Frequently rearranged in advanced T-cell lymphomas | FRAT1 | 2.72 |
AV756141 | Colony stimulating factor 2 receptor beta | CSF2RB | 2.71 |
NM_006019.1 | T-cell, immune regulator 1 | TCIRG1 | 2.59 |
J02959.1 | Leukotriene A-4 hydrolase | LTA4H | 2.59 |
BC004188.1 | Tubulin, beta, 2 | TUBB2 | 2.57 |
NM_001780.1 | CD63 antigen | CD63 | 2.53 |
NM_003254.1 | Tissue inhibitor of metalloproteinase 1 | TIMP1 | 2.37 |
AF070673.1 | Stannin | SNN | 2.35 |
BC003570.1 | Similar to vesicle-associated membrane protein 3 | VAMP3 | 2.31 |