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Table 2 Immune-response related genes which were found to be significantly down-regulated in PBMCs of SARS patients. Level of expression is expressed in Fold change (average of fold changes of ten patients, S1-S10) as compared to that of control samples from normal human subjects (C1-C4).

From: Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome

Genbank ID

Description

Gene name

Fold change (S1-S10)

D13720.1

IL2-inducible T-cell kinase

ITK

3.64

AF288571.1

Lymphoid enhancer factor-1

LEF1

3.63

NM_005356.1

Lymphocyte-specific protein tyrosine kinase

LCK

3.20

NM_003151.1

Signal transducer and activator of transcription 4

STAT4

3.14

BG435404

ADP-ribosylation factor-like 7

ARL7

2.99

J04132.1

T cell receptor zeta-chain

CD3Z

2.96

BG532690

Alpha 4 subunit of VLA-4 receptor

ITGA4

2.91

NM_001838.1

Chemokine (C-C motif) receptor 7

CCR7

2.83

AI743792

Sialyltransferase 1

SIAT1

2.71

NM_001558.1

Interleukin 10 receptor, alpha

IL10RA

2.71

BF669455

Sialomucin

CD164

2.58

NM_000733.1

Epsilon polypeptide of CD3

CD3E

2.58

AI073984

Interferon consensus sequence binding protein 1

ICSBP1

2.48

NM_005475.1

Lymphocyte adaptor protein

LNK

2.38

AB014560.

Ras-GTPase activating protein SH3 domain-binding protein 2

G3BP2

2.31

NM_004757.1

Small inducible cytokine subfamily E, member 1

SCYE1

2.19