Figure 6
T-cell proliferation results in hamsters immunized with the candidate HIV-1 gp120 vaccines. Splenocytes were cultured and stimulated with 10 μg/ml proteins of (6A): HIV-1 gp120 subtype B (MN strain), (6B): HIV-1 gp120 subtype B (SF162 strain), (6C): HIV-1 gp120 subtype C (96ZM651 strain), and (6D): HIV-1 gp120 subtype A/E (93TH975 strain). Two days later, 3H-thymidine was added and after 18 h the incorporated radioactivity was measured in harvested splenocytes. The stimulation index (SI) ± S.E. is shown for each group. Symbol * indicates a significant difference between group D with groups B and C (p ≤ 0.05).