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Figure 8 | BMC Immunology

Figure 8

From: Mycobacterium tuberculosis 6-kDa Early Secreted Antigenic Target (ESAT-6) protein downregulates Lipopolysaccharide induced c-myc expression by modulating the Extracellular Signal Regulated Kinases 1/2

Figure 8

ESAT-6 downregulated LPS-induced expression of several genes. (A-E) RT-PCR for the genes IL-1β, Bax, Icam-1, Tnfr-1 and β-actin. The data is representative of two independent experiments. Lane.1. Unstimulated cells, Lane.2. Cells stimulated with 5 μg/ml ESAT-6, Lane.3. Cells stimulated with 0.1 μg/ml of LPS, Lane.4. Cells stimulated with LPS and ESAT-6. (F) RT-PCR for β-actin to confirm equal amplification in all the samples.

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