Effects of Tlr4 mutation in vaccine-induced immunity. Parameters that show a lower response in Tlr4-deficient mice compared to wild-type animals are represented in red, while the ones that show a higher response are represented in green. Parameters that are not affected or have not been determined are represented in black. Triangles represent wP, circles aP, and squares B. pertussis. IL-23 is put between brackets as this cytokine is able to maintain, rather than generate Th17 cells.