Figure 4From: Methylprednisolone inhibits interleukin-17 and interferon-gamma expression by both naive and primed T cellsThe effect of IFN-γ addition or neutralization on the inhibition of IL-17 production by MP. LNC were stimulated with ConA (2.5 μg/ml) and incubated with or without MP (10 ng/ml) and/or IFN-γ (IFN – 100 ng/ml), and/or anti-IFN-γ-neutralizing antibody (a-IFN – 1 μg/ml) or isotype control antibody (a-Iso – 1 μg/ml) for 24 hours. Subsequently, culture supernatants were collected for ELISA and IL-17 (A) and IFN-γ(B) production was determined. *p < 0.05 represents statistically significant difference to control cultures (medium).Back to article page