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Table 1 Murine immune responses to HK vaccination

From: Host immunity in the protective response to vaccination with heat-killed Burkholderia mallei

Vaccine Pre-exposure Post-exposure
  IgG2a IgG1 Ratio IgG2a IgG1 Ratio
HK i.n. 0.00 0.07 + .005 0.00 0.88 + .031 1.46 + .027 0.60
HK i.p. 0.01 + .012 0.23 + .015 0.04 1.04 + .037 0.92 + .0005 1.13
HK i.p. CVF 0.01 + .002 0.13 + .004 0.07 1.42 + .020 1.02 + .002 1.39
None 0.00 0.00 0.00 0.86 + .025 1.01 + .002 0.85
  1. Samples were tested in duplicate and optical densities (OD) read at 450 nm. Values are reported as mean (± S.E.M.). n = 5 for pre-exposure and n = 2 for post exposure. CVF; cobra venom factor.