Figure 1
From: T lymphocytes maintain structure and function of fibroblastic reticular cells via lymphotoxin (LT)-B
The conduits of FRCs were destroyed in the absence of T cells. Spleen cryostat sections from BALB/c mice (A) and nude mice (B) were stained for ER-TR7 (red = FRC-derived matrix protein), and imaged using confocal microscopy (Scale bars: 200um); Arrows show a higher magnification of the marginal zone of spleen from BALB/c mice (C) and nude mice (D) (Scale bars: 50um); We further analyzed the average fluorescence values of ER-TR7 (E). Data are representative of 5 mice per group.