Figure 5

Transfusion of T cells restored the homing-to-spleen ability of T cells and could be blocked by the antibody against the LT-B recepto rs. After 4 weeks of transfusions of T cells naive T cells were purified and labeled with CFSE (green) and transferred into BALB/c, nude mice, nude mice + T cells and nude mice + T cells + anti-LtB, and their localization in the spleen was ascertained 8 hours later (Scale bars: 50um), (A), Quantitation of CFSE + cells in the spleen white pulps after transfer, (B), Percentages of CFSE + cells in spleen were determined by FACS, (C,D). Data are representative of 5 mice per group.