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Figure 1 | BMC Immunology

Figure 1

From: Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes

Figure 1

Principle Component Analysis and Volcano Plots of transcripts expressed in the spleens of uninfected or infected hamsters. A, C, E. Principle Component Analysis of uninfected and infected spleen tissue at 7 days (A), 14 days (C), and 28 days (E) post-infection. The groups of uninfected samples are circled in blue and infected samples are circled in red. The Cy3 and Cy5 dyes are represented by green and red symbols, respectively. Dye-swap arrays (files 11 and 12 for each time point) from pooled samples clustered appropriately within the corresponding infection status. B, D, F. Volcano plots showing the mean fold-change and p-value for the comparisons of uninfected and infected spleen tissue at 7 days (B), 14 days (D) and 28 days (F) post-infection. Red triangles show a fold-change >1 and blue triangles show a fold-change <1.

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BMC Immunology

ISSN: 1471-2172

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