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Figure 3 | BMC Immunology

Figure 3

From: Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes

Figure 3

Upregulation of Interferon-γ-inducible genes in the spleens of 28-day infected hamsters. (A) Schematic representation of the IFN-γ pathway with notation of interferon-γ-inducible genes found by microarray to be upregulated in the spleens of hamsters at 28 days post-infection. The fold-increase of the mRNA in the infected tissue is shown in blue in parentheses. (B) Expression of interferon-γ-inducible genes in the spleens of 28-day infected hamsters determined by real time RT-PCR. Data are shown as the mean and standard error of the mean (error bars) of the fold-increase in infected compared to uninfected animals (n = 5 per group). ***p≤0.001.

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BMC Immunology

ISSN: 1471-2172

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