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Table 3 Genes included in the "Immune Response" and "Inflammatory Response" Gene Ontology functions from differentially expressed genes after 28 days of infection

From: Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes

Immune response

Inflammatory response

Gene symbol

Fold-change

p-value

Gene symbol

Fold-change

p-value

Ifng

1748.95

9.71E-05

Ccl11

1212.26

0.00035

Ccl11

1212.26

0.00035

Ccl20

749.90

0.00133

Ccl20

749.90

0.00134

Cxcl1

488.25

4.04E-05

Igha1

653.51

8.07E-06

Reg3g

348.91

6.26E-05

Cxcl5

653.22

1.28E-04

Chst4

197.33

3.52E-05

Csf3

509.58

8.54E-06

Cdo1

45.39

0.0001

Cxcl1

488.25

4.04E-05

Cxcl9

35.64

7.46E-06

Azgp1

234.93

2.52E-05

Ccl17

16.36

0.020

Chst4

197.33

3.52E-05

Ccr5

13.75

3.60E-05

Cxcl9

35.64

7.46E-06

Cxcl10

12.16

2.25E-05

Ccl17

16.36

0.020

Fpr2

10.12

0.00073

Il21

14.64

6.74E-04

Il1rn

9.50

0.00026

Ccr5

13.75

3.60E-05

Hrh1

8.74

0.005

Cxcl10

12.16

2.25E-05

Aoah

6.33

0.00011

Gbp2

9.86

1.45E-05

Kng1

5.25

0.012

Cst7

9.53

0.00038

C5

5.17

0.022

Il1rn

9.50

0.00026

Cybb

4.97

0.00011

IL4

9.18

2.62E-05

IL10

4.57

0.00092

IL2Ra

8.15

0.0009

Mif

4.55

0.0117

Cd8a

6.73

0.0185

IL6

4.50

0.00059

Oasl

6.12

1.12E-04

Ccl22

3.68

0.00092

IL2

4.75

0.0122

Cxcl2

3.44

0.00723

Gzma

4.28

4.24E-04

Cxcl3

3.38

0.00965

Igsf6

4.15

0.0121

Lipa

3.02

8.24E-05

Il12a

4.14

0.0185

C3

2.96

2.79E-05

Ctss

3.88

0.0021

Slc11a1

2.72

1.04E-05

Igha1

3.79

4.57E-05

Tirap

2.28

0.00035

Tlr2

3.73

0.0018

Nlrp3

2.07

0.0166

Ccl22

3.68

0.00092

   

Ctss

3.52

0.0134

   

CD86

3.45

0.00068

   

Cxcl2

3.44

0.0072

   

Cxcl3

3.38

0.0096

   

Col4a3bp

3.26

0.00036

   

C3

2.96

2.79E-05

   

Map4k2

2.65

0.00011

   

Cmklr1

2.62

4.95E-05

   

Hfe

2.51

0.00168

   

Gem

2.50

0.00169

   

Osm

2.39

0.0034

   

Pnp

2.17

0.0031

   

Ikbke

2.06

0.00073

   

Map4k2

–2.07

0.0045

   

Cxcl12

–2.72

0.00015

   

Tinagl1

–2.88

0.0065

   

Ppbp

–3.29

5.52E-05

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