Figure 8
Experimental design. We studied a kidney transplant allogeneic model (Fisher to Lewis, 20 rats). 10 allografted rats (group B) were infused into the renal artery soon after graft reperfusion only with saline. 10 allografted rats (group C) were infused into the renal artery with 3±106MSC in 1 ml of PBS soon after graft reperfusion. Bilateral nephrectomy was performed in all rats soon before transplantation. 5 healthy rats (Lewis) were the control group (group A). No immunosuppressive therapy was administered. Blood was drawn from the caudal vein at day 0 (the day of transplantation, before the surgery), and at day 7. All the rats were sacrificed at day 7. A: healthy rats. B: allografted rats treated with saline, C: allografted rats treated with MSC.