Figure 3

Comparison of arthritis severity in a DBA/1^−/−(A, B) and Congenic DBA.B-1^−/−mice (C, D). Panels A and C are cross section of the ankle joint. Panels B and D are higher power views to illustrate the development of an early erosion in the DBA.B-1^−/− mouse whereas the comparable area of the DBA/1^−/− mouse shows only synovitis without erosive disease.