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Table 4 Genes associated with T-cell types

From: In silico analysis of autoimmune diseases and genetic relationships to vaccination against infectious diseases

 

RA

SLE

ITP

GBS

All four AIDs

Cytotoxic T cell (n = 13)

7

8

1

1

7

Exhausted T cell (n = 7)

4

5

0

0

6

Anergic T cell (n = 11)

4

2

0

0

5

TR1 cell (n = 9)

4

4

1

2

5

Natural TReg cell (n = 15)

8

8

2

3

9

Inducible TReg cell (n = 17)

8

8

2

3

9

NKT cell (n = 10)

6

5

2

1

10

CD8αα T cell (n = 10)

7

7

1

1

8

CD4+ αβ T cell (n = 10)

3

4

1

1

4

CD8+ αβ T cell (n = 9)

3

4

0

0

3

TH1 cell (n = 14)

8

9

3

4

10

TH 2 cell (n = 19)

8

8

2

2

10

TH 9 cell (n = 8)

3

4

1

2

4

TH 17 cell (n = 20)

11

5

1

1

12

TH 22 cell (n = 8)

3

3

1

1

4

TFH cell (n = 16)

9

10

2

3

13

Central memory T cell (n = 18)

7

10

3

1

10

Effector memory T cell (n = 8)

2

5

0

0

5

γδ T cell (n = 10)

5

4

1

1

7

  1. Genes for the surface phenotype, transcription factors, secreted effector molecules and other functions of different classes of T-cells were identified for each AID. The number in parentheses next to the cell type represents the total possible for each cell type. The number in each cell represents the number present in the AID gene set.