Table 1 Summary of microRNA changes in paired colon biopsies from Crohn’s disease and ulcerative colitis subjects
From: MicroRNA signatures differentiate Crohn’s disease from ulcerative colitis
Crohn’s disease | Ulcerative colitis | |||||
|---|---|---|---|---|---|---|
miRNA | N (Pairs) | Reduced ( p -value) | Elevated ( p -value) | N (Pairs) | Reduced ( p -value) | Elevated ( p -value) |
miR-19a | 10 | 6 (0.050)* | 4 (0.307) | 7 | 3 (0.136) | 4 (0.059) |
miR-21 | 10 | 4 (0.082) | 6 (0.024)* | 7 | 2 (0.203) | 5 (0.029)* |
miR-26a | 10 | 7 (0.064) | 3 (0.186) | 7 | 3 (0.072) | 4 (0.131) |
miR-31 | 10 | 1 (ND) | 9 (0.002)* | 7 | 0 (ND) | 7 (0.177) |
miR-101 | 10 | 5 (0.043) | 5 (0.041)* | 7 | 1 (ND) | 6 (0.023)* |
miR-142-3p | 10 | 2 (0.096) | 8 (0.018)* | 7 | 1 (ND) | 6 (0.053) |
miR-142-5p | 10 | 2 (0.133) | 8 (0.032)* | 7 | 0 (ND) | 7 (0.017)* |
miR-146a | 10 | 4 ( 0.121) | 6 (0.148) | 7 | 0 (ND) | 7 (0.015)* |
miR-155 | 10 | 4 (0.073) | 6 (0.024)* | 7 | 0 (ND) | 7 (0.016)* |
miR-223 | 10 | 1 (ND) | 9 (0.006)* | 7 | 0 (ND) | 7 (0.006)* |
miR-375 | 10 | 2 (0.353) | 8 (0.023)* | 7 | 3 (0.174) | 4 (0.060) |
miR-494 | 10 | 5 (0.136) | 5 (0.048)* | 7 | 2 (0.094) | 5 (0.134) |