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Table 1 Summary of microRNA changes in paired colon biopsies from Crohn’s disease and ulcerative colitis subjects

From: MicroRNA signatures differentiate Crohn’s disease from ulcerative colitis

  Crohn’s disease Ulcerative colitis
miRNA N (Pairs) Reduced ( p -value) Elevated ( p -value) N (Pairs) Reduced ( p -value) Elevated ( p -value)
miR-19a 10 6 (0.050)* 4 (0.307) 7 3 (0.136) 4 (0.059)
miR-21 10 4 (0.082) 6 (0.024)* 7 2 (0.203) 5 (0.029)*
miR-26a 10 7 (0.064) 3 (0.186) 7 3 (0.072) 4 (0.131)
miR-31 10 1 (ND) 9 (0.002)* 7 0 (ND) 7 (0.177)
miR-101 10 5 (0.043) 5 (0.041)* 7 1 (ND) 6 (0.023)*
miR-142-3p 10 2 (0.096) 8 (0.018)* 7 1 (ND) 6 (0.053)
miR-142-5p 10 2 (0.133) 8 (0.032)* 7 0 (ND) 7 (0.017)*
miR-146a 10 4 ( 0.121) 6 (0.148) 7 0 (ND) 7 (0.015)*
miR-155 10 4 (0.073) 6 (0.024)* 7 0 (ND) 7 (0.016)*
miR-223 10 1 (ND) 9 (0.006)* 7 0 (ND) 7 (0.006)*
miR-375 10 2 (0.353) 8 (0.023)* 7 3 (0.174) 4 (0.060)
miR-494 10 5 (0.136) 5 (0.048)* 7 2 (0.094) 5 (0.134)
  1. ND, not determined due to insufficient number of samples in group.
  2. *statistically significant values, p < 0.05.