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Figure 2 | BMC Immunology

Figure 2

From: C-reactive protein enhances activation of coagulation system and inflammatory response through dissociating into monomeric form in antineutrophil cytoplasmic antibody-associated vasculitis

Figure 2

Representative images of the depositions of platelets and mCRP on the immobilized ANCA-induced netting neutrophils (×100). pCRP (60 μg/mL)-containing PRP was used in all groups. DNA was stained as a marker of netting neutrophils using DAPI (blue). Bright spots were neutrophils without NETs formation while cloud-like structures were NETs. Activated platelets were stained using FITC conjugated anti-CD62P mAb (green). Deposited mCRP was stained using Clone CRP-8 and TRITC-goat anti-mouse antibodies (red). All experiments were performed in triplicate. Scale bar: 50 μm.

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